{"id":"W2765718728","doi":"10.1038/s41598-017-14229-8","title":"Leishmania infantum lipophosphoglycan induced-Prostaglandin E2 production in association with PPAR-γ expression via activation of Toll like receptors-1 and 2","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Fundação de Amparo à Pesquisa do Estado da Bahia; Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Proinflammatory cytokine; Lipophosphoglycan; Chemistry; Leishmania infantum; Cell biology; Prostaglandin E2; Biology; Immunology; Endocrinology; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001728105,0.0003921876,0.0002464962,0.000306594,0.0001151998,0.0002609118,0.0001082426,0.0002901147,0.001621037],"category_scores_gemma":[0.0001288421,0.0001368267,0.0002661549,0.0001923258,0.0002281612,0.0001655639,0.000271753,0.0004764977,0.000409289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001449012,"about_ca_system_score_gemma":0.0001662175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002166161,"about_ca_topic_score_gemma":0.0002477879,"domain_scores_codex":[0.9998475,0.00004404779,0.0000115427,0.00001614729,0.0000293757,0.00005139867],"domain_scores_gemma":[0.9999233,0.00001083259,0.00002463139,0.000008635728,0.00001366571,0.00001882426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003667392,0.00006063834,0.0002540939,0.0001306929,0.000005056683,0.0002033263,0.00002158503,0.00002074774,0.9980008,0.00005673619,0.00006007803,0.0008193632],"study_design_scores_gemma":[0.0001525405,0.001276667,0.02436609,0.00004787852,0.00004861144,0.001034462,0.000202613,0.0009278675,0.9682232,0.0002625801,0.003441904,0.00001553401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916681,0.003413311,0.002050098,0.0003411184,0.00008844724,0.00007704733,0.0004741661,0.00006827767,0.001819434],"genre_scores_gemma":[0.9937424,0.001628111,0.001400381,0.0002091438,0.00003792419,0.000100658,0.0004570954,0.000008757102,0.0024155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001621037,"threshold_uncertainty_score":0.00542289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02137501802662996,"score_gpt":0.2862490576587167,"score_spread":0.2648740396320868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}