{"id":"W2765902885","doi":"10.1016/j.brainres.2017.10.015","title":"Investigating the efficacy of a combination Aβ-targeted treatment in a mouse model of Alzheimer’s disease","year":2017,"lang":"en","type":"article","venue":"Brain Research","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Ontario Brain Institute; Sunnybrook Health Science Centre","funders":"National Institute of Biomedical Imaging and Bioengineering","keywords":"Disease; Alzheimer's disease; Neuroscience; Medicine; Psychology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000560195,0.001027449,0.001491727,0.001132913,0.0004136283,0.0006395213,0.0007508054,0.0012868,0.001201325],"category_scores_gemma":[0.0002073852,0.0003519799,0.0009000053,0.0005135814,0.0006308336,0.0008915178,0.0002414431,0.002285357,0.0004591864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003900868,"about_ca_system_score_gemma":0.00048128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007814431,"about_ca_topic_score_gemma":0.001250977,"domain_scores_codex":[0.9995908,0.00005163837,0.00004423642,0.0001080397,0.00009343147,0.0001118412],"domain_scores_gemma":[0.9997038,0.00003074918,0.0000611842,0.00004014452,0.00004367369,0.00012048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01007887,0.003824163,0.0004639199,0.000249068,0.0001777576,0.0002020152,0.00006203484,0.0003475552,0.9731143,0.000263265,0.0005058683,0.01071112],"study_design_scores_gemma":[0.00260039,0.06405029,0.004975218,0.00005989014,0.0009276731,0.0008109387,0.0001593179,0.002270772,0.9148354,0.0004933601,0.008758593,0.00005821371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913777,0.004125992,0.001640672,0.0003505389,0.0003858415,0.0001436146,0.0005336503,0.0001161255,0.001325838],"genre_scores_gemma":[0.9851782,0.005081387,0.003406614,0.0002490052,0.000189496,0.0004037436,0.0008718909,0.00004741881,0.004572121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001491727,"threshold_uncertainty_score":0.004018843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.187392778545254,"score_gpt":0.4361616276753804,"score_spread":0.2487688491301264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}