{"id":"W2765944252","doi":"10.1039/c7an00744b","title":"Tip-enhanced Raman spectroscopy of amyloid β at neuronal spines","year":2017,"lang":"en","type":"article","venue":"The Analyst","topic":"Spectroscopy Techniques in Biomedical and Chemical Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Synapse; Context (archaeology); Pathogenesis; Raman spectroscopy; Neuroscience; Chemistry; Biophysics; Amyloid (mycology); Glutamate receptor; Biology; Biochemistry; Physics; Receptor; Optics; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001948569,0.0001091391,0.0001538872,0.00002143367,0.0002374834,0.00002815983,0.0009077475,0.00008862196,0.0001955119],"category_scores_gemma":[0.0001693779,0.00006963728,0.0001291173,0.00005078471,0.0006313782,0.000002537404,0.0005286048,0.0001173985,0.00001784772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001548743,"about_ca_system_score_gemma":0.000028965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004603368,"about_ca_topic_score_gemma":0.00002791778,"domain_scores_codex":[0.9990647,0.0000286194,0.0001669181,0.0002421048,0.0002537497,0.0002438492],"domain_scores_gemma":[0.9987782,0.00001343463,0.0001262949,0.0009436745,0.00006129973,0.00007710447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001054831,0.00003221883,0.0008326981,0.000009573701,0.00003900409,0.000001004895,0.000004871053,2.994379e-7,0.9918551,0.0001105432,0.006708166,0.0003009912],"study_design_scores_gemma":[0.0001666151,0.0001909655,0.003801855,0.000009206359,0.00001715249,0.000002448636,0.00000498501,0.00001845811,0.9750532,0.0005472135,0.02010864,0.00007926884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804162,0.0001878601,0.001284531,0.0009637657,0.00005052508,0.00008746255,0.00001108424,0.00001107359,0.01698745],"genre_scores_gemma":[0.9948712,0.0003935267,0.0005190783,0.0001535679,0.0002755245,0.00001206802,0.000031132,0.00001161367,0.003732278],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01680196,"threshold_uncertainty_score":0.2839726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01391694741814079,"score_gpt":0.3355602679462294,"score_spread":0.3216433205280886,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}