{"id":"W2765963118","doi":"10.18632/aging.101303","title":"Age-related decline of the acute local inflammation response: a mitigating role for the adenosine A2A receptor","year":2017,"lang":"en","type":"article","venue":"Aging","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"CXCL1; Inflammation; Immunology; Adenosine A2A receptor; Cytokine; Neutrophil elastase; Elastase; Receptor; Knockout mouse; Internal medicine; Chemokine; Endocrinology; Biology; Adenosine receptor; Medicine; Biochemistry; Agonist","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004480637,0.00008971034,0.00009064974,0.00001245909,0.00045207,0.00004111175,0.0003911904,0.00007819867,0.000008853671],"category_scores_gemma":[0.0003745671,0.00005663389,0.00009720217,0.00003613887,0.0001487199,0.00000660142,0.0002185538,0.00008292256,0.00000153183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007179212,"about_ca_system_score_gemma":0.00004324655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000394578,"about_ca_topic_score_gemma":0.000009080006,"domain_scores_codex":[0.9993497,0.00005605217,0.0002074963,0.0001487271,0.00009509538,0.0001429909],"domain_scores_gemma":[0.9991117,0.00008817348,0.000245988,0.0004554659,0.00007720104,0.00002149121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002013934,0.000007313428,0.001311172,0.00001113056,0.0001148435,9.011746e-7,0.0002402565,0.0006546502,0.9893411,0.0001135638,0.002062285,0.005941352],"study_design_scores_gemma":[0.0007520206,0.00007749062,0.006756028,0.00008655347,0.00008643247,0.000008339773,0.0002126814,0.002578767,0.9678115,0.0002850626,0.0212239,0.0001212128],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878886,0.001081092,0.005363861,0.005131002,0.0001600098,0.0002234188,0.00001060511,0.00000746752,0.0001339889],"genre_scores_gemma":[0.9980787,0.00003263368,0.0005246198,0.0001358348,0.0002693293,0.00002067642,0.00002591694,0.00001551693,0.0008967913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02152963,"threshold_uncertainty_score":0.3477003,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009020959905348161,"score_gpt":0.2681461654240081,"score_spread":0.2591252055186599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}