{"id":"W2766173255","doi":"10.1016/j.micpath.2017.10.037","title":"Enterotoxigenic Escherichia coli targeting intestinal epithelial tight junctions: An effective way to alter the barrier integrity","year":2017,"lang":"en","type":"review","venue":"Microbial Pathogenesis","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Enterotoxigenic Escherichia coli; Tight junction; Enterotoxin; Heat-stable enterotoxin; Microbiology; Intestinal epithelium; Epithelium; Escherichia coli; Biology; Claudin; Caco-2; Cell biology; Chemistry; Cell; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0008832637,0.0009941227,0.001728467,0.0002515014,0.002346452,0.0004988846,0.001557705,0.0004270133,0.0002375641],"category_scores_gemma":[0.002321118,0.0006254694,0.0009403693,0.0005082666,0.0004426603,0.0002662633,0.0007511684,0.001225887,0.0006055108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002326311,"about_ca_system_score_gemma":0.0001854466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000868049,"about_ca_topic_score_gemma":0.0001005582,"domain_scores_codex":[0.9947417,0.001694361,0.0008874945,0.001558579,0.0003576899,0.0007601589],"domain_scores_gemma":[0.9970062,0.0005092775,0.0006765776,0.001296742,0.0002010608,0.0003101645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009309685,0.00007462167,0.00001255953,0.0009256205,0.0001280383,0.00003943401,0.0004944512,8.553886e-7,0.1904238,0.00004189946,0.004125915,0.8036398],"study_design_scores_gemma":[0.0001981613,0.0002215369,0.00009438468,0.001109506,0.0006655976,0.0001179144,0.00003217671,0.00000238887,0.01294546,0.00002595551,0.9838858,0.0007010964],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007602178,0.9582907,0.002845364,0.0001842855,0.01855461,0.008880514,0.002297859,0.0004477322,0.0008967841],"genre_scores_gemma":[0.004268833,0.9765927,0.001438413,0.002685746,0.007485806,0.003668572,0.0001234083,0.0004151473,0.003321444],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9797599,"threshold_uncertainty_score":0.9996197,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06840372895246358,"score_gpt":0.3319787295695129,"score_spread":0.2635750006170493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}