{"id":"W2766175045","doi":"10.1002/cncr.31082","title":"Long‐term patient‐reported outcomes from an open‐label safety and efficacy study of bosutinib in Philadelphia chromosome–positive chronic myeloid leukemia patients resistant or intolerant to prior therapy","year":2017,"lang":"en","type":"article","venue":"Cancer","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Ariad Pharmaceuticals; Pfizer","keywords":"Medicine; Cohort; Internal medicine; Bosutinib; Quality of life (healthcare); Myeloid leukemia; Cancer; Visual analogue scale; Oncology; Nilotinib; Imatinib; Physical therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004192804,0.0006833419,0.001250995,0.0004092067,0.0005694417,0.001079738,0.0004545169,0.00094499,0.001836475],"category_scores_gemma":[0.002602187,0.0002795516,0.001765105,0.0005793193,0.0007099085,0.0008616938,0.0006364526,0.001989017,0.0003270672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007640782,"about_ca_system_score_gemma":0.0008978102,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007008029,"about_ca_topic_score_gemma":0.001207084,"domain_scores_codex":[0.9988157,0.0005475208,0.0001158191,0.0001436373,0.0002439394,0.0001334354],"domain_scores_gemma":[0.9952779,0.0008219056,0.002151175,0.0002595294,0.0004067485,0.001082781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6244498,0.02942743,0.2283303,0.001798722,0.009336414,0.0004206468,0.0005931431,0.002021492,0.008114441,0.0002133819,0.005066841,0.09022747],"study_design_scores_gemma":[0.1590792,0.2301454,0.5967887,0.000252409,0.004343622,0.0005740144,0.0003424161,0.002747825,0.001850961,0.0002180875,0.003548474,0.0001089035],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995962,0.001611217,0.0001393515,0.0001478348,0.00003417581,0.0003414912,0.001235735,0.000008403888,0.0005198377],"genre_scores_gemma":[0.9951508,0.0006621244,0.0001792749,0.0003265638,0.0001114573,0.0006512887,0.002634903,0.000003438012,0.0002800743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004192804,"threshold_uncertainty_score":0.02217388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05714009683101398,"score_gpt":0.3696422830219721,"score_spread":0.312502186190958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}