{"id":"W2766196487","doi":"10.1021/acsinfecdis.7b00105","title":"Marine Mammal Microbiota Yields Novel Antibiotic with Potent Activity Against <i>Clostridium difficile</i>","year":2017,"lang":"en","type":"article","venue":"ACS Infectious Diseases","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"National Institute of General Medical Sciences; Office of Research on Women's Health; National Institute of Child Health and Human Development; University of Illinois at Chicago; Division of Graduate Education; University of Illinois at Urbana-Champaign; University of California, San Francisco; Division of Molecular and Cellular Biosciences; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Biology; Microbiology; Antibiotics; Gut flora; Clostridium difficile; Pathogen; Human pathogen; Commensalism; Antimicrobial; Bacteria; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008834958,0.0002633252,0.0001565014,0.0001809886,0.0001103058,0.0002070347,0.0001004557,0.0001819758,0.0008489948],"category_scores_gemma":[0.0001159836,0.00006743072,0.0001499629,0.0001429751,0.00009210721,0.0001489279,0.0002118258,0.0002649513,0.000256739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00010033,"about_ca_system_score_gemma":0.0001498633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004129278,"about_ca_topic_score_gemma":0.001036504,"domain_scores_codex":[0.9999306,0.00001244815,0.000004775489,0.00001518122,0.00001956601,0.00001746442],"domain_scores_gemma":[0.9999623,0.000004115145,0.00001072446,0.0000033683,0.000006930972,0.00001258016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007806531,0.00002643038,0.0003024777,0.00004926523,0.000004660259,0.0000597795,0.00001144873,0.00005366389,0.9947762,0.00003115332,0.00007804097,0.004528889],"study_design_scores_gemma":[0.00001284138,0.001209837,0.008170083,0.00001962636,0.00002766025,0.0003636858,0.00004423903,0.000317811,0.9827757,0.00003432466,0.007017214,0.000006860169],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893365,0.003081115,0.001981083,0.0001555628,0.00003644719,0.00004528056,0.0005949768,0.0001176302,0.004651478],"genre_scores_gemma":[0.9918265,0.001613761,0.003931762,0.0001248744,0.00001276207,0.00001115533,0.0005858971,0.00002179131,0.00187139],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008489948,"threshold_uncertainty_score":0.002840221,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01756328370576007,"score_gpt":0.271423916420213,"score_spread":0.253860632714453,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}