{"id":"W2766196487","doi":"10.1021/acsinfecdis.7b00105","title":"Marine Mammal Microbiota Yields Novel Antibiotic with Potent Activity Against <i>Clostridium difficile</i>","year":2017,"lang":"en","type":"article","venue":"ACS Infectious Diseases","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"National Institute of General Medical Sciences; Office of Research on Women's Health; National Institute of Child Health and Human Development; University of Illinois at Chicago; Division of Graduate Education; University of Illinois at Urbana-Champaign; University of California, San Francisco; Division of Molecular and Cellular Biosciences; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Biology; Microbiology; Antibiotics; Gut flora; Clostridium difficile; Pathogen; Human pathogen; Commensalism; Antimicrobial; Bacteria; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001460949,0.0005912934,0.0007574916,0.000242082,0.001114472,0.0004199668,0.0004889421,0.0002608723,0.000172239],"category_scores_gemma":[0.00052982,0.0004832342,0.0003192323,0.0002707158,0.0005916284,0.0002784775,0.0006640955,0.0007336936,0.0001564085],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003894755,"about_ca_system_score_gemma":0.0005957436,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007535439,"about_ca_topic_score_gemma":0.0001964343,"domain_scores_codex":[0.9969272,0.00004751878,0.0003646935,0.0009087321,0.0007553628,0.0009965004],"domain_scores_gemma":[0.9965497,0.0001370564,0.0003107843,0.001931724,0.0003706938,0.0007000096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002272168,0.00663449,0.3549367,0.0005907903,0.0007845065,0.001083582,0.00003682475,0.0000635619,0.5967774,0.000122635,0.003813076,0.03288428],"study_design_scores_gemma":[0.008744243,0.001866698,0.4877549,0.0004198127,0.0008005453,0.0005905461,0.00005411868,0.0001594345,0.4952658,0.00001417084,0.003374601,0.0009551654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807585,0.0001482753,0.0000693594,0.002064888,0.0003594224,0.0009703436,0.0002897718,0.0003126994,0.01502667],"genre_scores_gemma":[0.9965589,0.0004971655,0.00005889112,0.0003815754,0.0007388754,0.00003265069,0.0001438367,0.0001097877,0.001478291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1328181,"threshold_uncertainty_score":0.9997619,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01756328370576007,"score_gpt":0.271423916420213,"score_spread":0.253860632714453,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}