{"id":"W2766222490","doi":"10.1002/humu.23361","title":"<i>DCC</i>mutation update: Congenital mirror movements, isolated agenesis of the corpus callosum, and developmental split brain syndrome","year":2017,"lang":"en","type":"review","venue":"Human Mutation","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre; Montreal Neurological Institute and Hospital","funders":"Dystonia Coalition; National Health and Medical Research Council; Medical Research Council; Ipsen; National Institute of Neurological Disorders and Stroke; Merz Pharmaceuticals; European Academy of Neurology; Universiteit Leiden; Leids Universitair Medisch Centrum; Amadys; Australian Government; State Government of Victoria; Intellectual and Developmental Disabilities Research Center; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Boston Children's Hospital; National Institutes of Health","keywords":"Biology; Deleted in Colorectal Cancer; Missense mutation; Agenesis of the corpus callosum; Netrin; Loss function; Genetics; Phenotype; Mutation; Corpus callosum; Gene; Axon guidance; Neuroscience; Receptor; Cancer; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000309978,0.0007718027,0.0008235517,0.003133522,0.0002868309,0.0008420352,0.0008152723,0.001319951,0.006090784],"category_scores_gemma":[0.001083542,0.0002222379,0.0004664722,0.001494552,0.0003016223,0.0008549893,0.0007518754,0.0008014056,0.005566265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004685761,"about_ca_system_score_gemma":0.0005263246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001676781,"about_ca_topic_score_gemma":0.003713191,"domain_scores_codex":[0.9996989,0.0000246436,0.00008174132,0.00004598107,0.0001169475,0.00003191039],"domain_scores_gemma":[0.9994606,0.0001525988,0.0000896061,0.00001950107,0.000190357,0.0000873171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001285183,0.00004235981,0.003768699,0.00287079,0.0001447873,0.01069839,0.000123801,0.0003051503,0.008299607,0.001102056,0.4795366,0.4929793],"study_design_scores_gemma":[0.0000139497,0.00003135026,0.005071905,0.0006915951,0.0001233559,0.04610343,0.00003951417,0.0001235039,0.002091922,0.0005390462,0.9451472,0.00002333182],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03110067,0.8101124,0.01327588,0.02418869,0.01610485,0.0002227614,0.01815247,0.005176981,0.08166523],"genre_scores_gemma":[0.0523911,0.7716678,0.02009255,0.02182268,0.01958944,0.0002185436,0.0490929,0.001250066,0.06387486],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006090784,"threshold_uncertainty_score":0.02037573,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.127545218377329,"score_gpt":0.3530140895753102,"score_spread":0.2254688711979812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}