{"id":"W2766317007","doi":"10.1002/glia.23245","title":"Mechanisms of lysophosphatidylcholine‐induced demyelination: A primary lipid disrupting myelinopathy","year":2017,"lang":"en","type":"article","venue":"Glia","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":208,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research","keywords":"Lysophosphatidylcholine; Endogeny; Myelin; Inflammation; Biology; Homeostasis; Clearance; Cell biology; Neuroscience; Immunology; Endocrinology; Medicine; Central nervous system; Biochemistry; Membrane; Phosphatidylcholine; Phospholipid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002312647,0.001078253,0.0004481682,0.0006394702,0.0002579634,0.0004569296,0.0003495851,0.0007441363,0.0008061911],"category_scores_gemma":[0.00009543411,0.0001251875,0.0003001513,0.0002387941,0.0007567742,0.0005507426,0.0003978441,0.0007713101,0.0003728678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006518849,"about_ca_system_score_gemma":0.0003455384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004551191,"about_ca_topic_score_gemma":0.0004325455,"domain_scores_codex":[0.9998403,0.00003081527,0.00001581603,0.00003366368,0.00003860337,0.00004079479],"domain_scores_gemma":[0.9999108,0.000005970571,0.00003719555,0.000007203387,0.00001409682,0.00002467378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003112282,0.00008905544,0.0008523748,0.0003444875,0.00001960246,0.001406464,0.00008026989,0.0001010796,0.9897255,0.00114931,0.0001657023,0.005754849],"study_design_scores_gemma":[0.00004150025,0.0009629979,0.008495288,0.00006811965,0.00007004861,0.006704198,0.0001627053,0.0003931286,0.9762802,0.001527572,0.005279036,0.00001523717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.914567,0.06044609,0.01856564,0.001324825,0.0001280918,0.0002292582,0.0004702326,0.0005777096,0.003691099],"genre_scores_gemma":[0.9628258,0.02858482,0.003799638,0.0002878257,0.00006498961,0.0001048304,0.0002039124,0.00002230984,0.004105927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001078253,"threshold_uncertainty_score":0.004729748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01587670761354635,"score_gpt":0.2686529793540984,"score_spread":0.2527762717405521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}