{"id":"W2766352605","doi":"10.1126/science.aao4815","title":"Atomic model for the dimeric F <sub>O</sub> region of mitochondrial ATP synthase","year":2017,"lang":"en","type":"article","venue":"Science","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":239,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute of General Medical Sciences; Canada Research Chairs; Simons Foundation","keywords":"ATP synthase; Adenosine triphosphate; Angstrom; Chemiosmosis; F-ATPase; Mitochondrion; Biophysics; Chemistry; Saccharomyces cerevisiae; Inner mitochondrial membrane; Crystallography; Membrane; Proton; ATPase; Cryo-electron microscopy; Biology; Biochemistry; Physics; Yeast; Enzyme; Gene; Chloroplast","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002472998,0.00007673582,0.00008160101,0.00002662986,0.0006601635,0.00006424701,0.0009142522,0.00004843144,9.703864e-7],"category_scores_gemma":[0.0005654853,0.0000531377,0.00008291324,0.00006061584,0.001139147,0.00001317415,0.0002681024,0.00004856207,0.000003742858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009578673,"about_ca_system_score_gemma":0.0002920535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001244553,"about_ca_topic_score_gemma":0.00001058597,"domain_scores_codex":[0.9990928,0.00001086183,0.0001061579,0.0003050122,0.0002180402,0.0002671391],"domain_scores_gemma":[0.9988586,0.00002967195,0.0001057943,0.0008126045,0.0001237231,0.00006954995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007823547,0.00001828932,0.00008347822,0.000006666552,0.00000598721,8.74108e-7,0.00002668955,0.0001524033,0.9912784,0.00008444259,0.0004972896,0.007767206],"study_design_scores_gemma":[0.0002598205,0.00008324148,0.0002919588,0.000009877264,0.000008522145,0.000002603277,0.00002191157,0.04998973,0.947883,0.0001509536,0.001221251,0.00007717368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9577197,0.0002144701,0.04109701,0.0003587006,0.0002253681,0.0002465076,0.0000130704,0.000003519633,0.0001216598],"genre_scores_gemma":[0.9988772,0.0001569691,0.0004819829,0.00005156187,0.0001710058,0.000033941,0.00000301557,0.000008143468,0.0002162055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04983733,"threshold_uncertainty_score":0.507751,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03604621928776763,"score_gpt":0.3272714500972131,"score_spread":0.2912252308094455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}