{"id":"W2766352605","doi":"10.1126/science.aao4815","title":"Atomic model for the dimeric F <sub>O</sub> region of mitochondrial ATP synthase","year":2017,"lang":"en","type":"article","venue":"Science","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":239,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute of General Medical Sciences; Canada Research Chairs; Simons Foundation","keywords":"ATP synthase; Adenosine triphosphate; Angstrom; Chemiosmosis; F-ATPase; Mitochondrion; Biophysics; Chemistry; Saccharomyces cerevisiae; Inner mitochondrial membrane; Crystallography; Membrane; Proton; ATPase; Cryo-electron microscopy; Biology; Biochemistry; Physics; Yeast; Enzyme; Gene; Chloroplast","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009238254,0.0003957176,0.0006545921,0.0002780577,0.001451949,0.0009052287,0.001823706,0.002561135,0.01435232],"category_scores_gemma":[0.0002518859,0.0003260619,0.000568034,0.0005064959,0.0006265646,0.0009547358,0.0005232395,0.001178032,0.002569357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008954117,"about_ca_system_score_gemma":0.0009165861,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008990534,"about_ca_topic_score_gemma":0.006179133,"domain_scores_codex":[0.9999462,0.000009321798,0.00000272002,0.000009732688,0.00001914632,0.00001273862],"domain_scores_gemma":[0.9999343,0.00001120618,0.000008826975,0.00001172221,0.00001456641,0.00001935472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0006085935,0.000192799,0.003276972,0.0005618139,0.00009547242,0.00231498,0.0009461529,0.3862912,0.06391637,0.4711899,0.04456956,0.02603599],"study_design_scores_gemma":[0.0004252852,0.0002347517,0.003451802,0.0001241548,0.00007080898,0.0008307941,0.0007212571,0.6627492,0.004260937,0.1937171,0.1333036,0.0001102441],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5184162,0.009954136,0.1942859,0.01937879,0.00209065,0.0002584018,0.008522249,0.004714285,0.2423794],"genre_scores_gemma":[0.908353,0.00256119,0.06230472,0.0008677542,0.0001203323,0.0002654633,0.003618061,0.000414913,0.02149462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01435232,"threshold_uncertainty_score":0.04801327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03604621928776763,"score_gpt":0.3272714500972131,"score_spread":0.2912252308094455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}