{"id":"W2766450925","doi":"10.1161/circ.134.suppl_1.13106","title":"Abstract 13106: Over Expression of Glyoxalase 1 Prevents Chronic Hyperglycemia Induced Explant Derived Cardiac Stem Cell Dysfunction","year":2016,"lang":"en","type":"article","venue":"Circulation","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Medicine; Stem cell; Lactoylglutathione lyase; Explant culture; Cardiology; Cell biology; Internal medicine; Methylglyoxal; In vitro; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001480298,0.000124026,0.0001232122,0.00005780736,0.00005642192,0.00000713599,0.0001007097,0.0001505458,0.00006893341],"category_scores_gemma":[0.00004250276,0.00009988423,0.00006791742,0.00008151937,0.00003073363,0.0000254715,0.00005438937,0.00006201117,0.00001843572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000926579,"about_ca_system_score_gemma":0.0001194717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006382653,"about_ca_topic_score_gemma":0.000001086867,"domain_scores_codex":[0.998904,0.00007444516,0.0002398793,0.0003611638,0.0002341077,0.0001863913],"domain_scores_gemma":[0.9991862,0.0000228124,0.000176205,0.000428568,0.0001201423,0.00006608957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000114885,0.0000380358,0.005209429,0.00005465823,0.00001214443,4.264409e-7,0.00002567033,0.0002610739,0.9760818,0.000004527625,0.0001063836,0.01809095],"study_design_scores_gemma":[0.0006570817,0.00006233761,0.124794,0.00004998142,0.000007461681,0.000001013034,0.00001325418,0.00001436461,0.872892,0.00002570774,0.001367488,0.0001153771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944924,0.0003461384,0.004362964,0.00002186117,0.0002177642,0.0002984344,0.00002922378,0.00001464551,0.0002166393],"genre_scores_gemma":[0.9990655,0.000168423,0.00009028071,0.000006941862,0.0002410944,0.00003301356,0.0001609502,0.00002344242,0.0002103161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1195845,"threshold_uncertainty_score":0.4073161,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01942177970552541,"score_gpt":0.2704548195981637,"score_spread":0.2510330398926383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}