{"id":"W2766663577","doi":"10.1200/jco.2017.35.15_suppl.5036","title":"Assessment of quality of life (QOL), cognitive function and depression in a randomized phase II study of abiraterone acetate (ABI) plus prednisone (P) vs enzalutamide (ENZA) for metastatic castrate-resistant prostate cancer (mCRPC).","year":2017,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer-related cognitive impairment studies","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Montreal Cognitive Assessment; Medicine; Enzalutamide; Quality of life (healthcare); Internal medicine; Prostate cancer; Depression (economics); Randomized controlled trial; Oncology; Physical therapy; Cognitive impairment; Cancer; Disease; Androgen receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002645779,0.001335328,0.002092839,0.0003608954,0.0004177428,0.0007973603,0.0007812309,0.001081082,0.005292282],"category_scores_gemma":[0.001807103,0.0007948084,0.001747657,0.0004882675,0.001008551,0.0006729057,0.0005092671,0.002205369,0.0006151625],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008127131,"about_ca_system_score_gemma":0.001596626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001133133,"about_ca_topic_score_gemma":0.002741748,"domain_scores_codex":[0.9989322,0.0006609609,0.0000569725,0.0001473667,0.00009526523,0.0001073494],"domain_scores_gemma":[0.9986607,0.0002935842,0.0003700653,0.00009137467,0.00007208106,0.0005122989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9761885,0.01093779,0.00191461,0.0002357588,0.0007346536,0.00002566052,0.00004870756,0.000293687,0.001703718,0.00003194832,0.0002863513,0.007598648],"study_design_scores_gemma":[0.8492201,0.1421062,0.007148074,0.00001563953,0.000514072,0.00003588852,0.00001809662,0.0003241178,0.0002507199,0.00005623996,0.0003002723,0.00001048112],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923801,0.001368923,0.0003635279,0.0002612145,0.0001330769,0.00377869,0.0008540641,0.00003184172,0.0008285685],"genre_scores_gemma":[0.9893318,0.0009908127,0.001008032,0.0004216475,0.000210892,0.005586628,0.001032131,0.000008548958,0.001409428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005292282,"threshold_uncertainty_score":0.01770449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1813795727884055,"score_gpt":0.539802924045878,"score_spread":0.3584233512574725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}