{"id":"W2766725373","doi":"10.1016/j.vaccine.2017.10.072","title":"Superior immunogenicity of HCV envelope glycoproteins when adjuvanted with cyclic-di-AMP, a STING activator or archaeosomes","year":2017,"lang":"en","type":"article","venue":"Vaccine","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"National Research Council Canada; University of Alberta","funders":"Alberta Innovates; University of Alberta","keywords":"Immunogenicity; Adjuvant; Neutralizing antibody; Immune system; Immunization; Antibody; Immunology; Virology; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002260237,0.0003047942,0.0006358595,0.0001478499,0.0005242242,0.00003554956,0.0007333309,0.0002096703,0.002229169],"category_scores_gemma":[0.0006671073,0.000200408,0.000117189,0.00007125296,0.0001596229,0.0002459743,0.0003795016,0.0003634014,0.0001925581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004229491,"about_ca_system_score_gemma":0.0001892444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001246346,"about_ca_topic_score_gemma":0.0005144363,"domain_scores_codex":[0.9984913,0.0001716142,0.0004454216,0.0003523696,0.00005760671,0.0004816864],"domain_scores_gemma":[0.9982075,0.0001733534,0.0003959492,0.001033705,0.0001569573,0.00003254546],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0158397,0.0001666095,0.01259816,0.00005516157,0.0005351051,0.00001762303,0.001364652,4.004325e-7,0.9562308,0.00007416723,0.0003331144,0.01278449],"study_design_scores_gemma":[0.00538716,0.001104438,0.1046201,0.0003242638,0.00006762354,0.0001755394,0.0003879663,0.000001887527,0.841802,0.00001810671,0.04578795,0.0003229545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996576,0.001279397,0.0001930681,0.0005309588,0.0002878336,0.0004336363,0.00006132582,0.00007907736,0.0005587807],"genre_scores_gemma":[0.9886382,0.0001203536,0.00052659,0.0000636219,0.00003676748,0.00003929139,0.00003965077,0.00004030193,0.01049527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1144288,"threshold_uncertainty_score":0.9986829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02389906791943569,"score_gpt":0.2705869970077663,"score_spread":0.2466879290883306,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}