{"id":"W2766725373","doi":"10.1016/j.vaccine.2017.10.072","title":"Superior immunogenicity of HCV envelope glycoproteins when adjuvanted with cyclic-di-AMP, a STING activator or archaeosomes","year":2017,"lang":"en","type":"article","venue":"Vaccine","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"National Research Council Canada; University of Alberta","funders":"Alberta Innovates; University of Alberta","keywords":"Immunogenicity; Adjuvant; Neutralizing antibody; Immune system; Immunization; Antibody; Immunology; Virology; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001960435,0.0002662704,0.0001437197,0.0001472583,0.00009239162,0.0002391511,0.0001016864,0.0002478375,0.0008111046],"category_scores_gemma":[0.0002766956,0.00008343205,0.0001368328,0.00008117034,0.0001858192,0.0002079172,0.0001545753,0.0003990643,0.0001773512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001771744,"about_ca_system_score_gemma":0.0002397447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003649277,"about_ca_topic_score_gemma":0.0004296827,"domain_scores_codex":[0.9998873,0.00003151014,0.00000737968,0.00001206417,0.00002159071,0.00004014423],"domain_scores_gemma":[0.9998978,0.00002626411,0.00002042648,0.00001512617,0.00001360785,0.00002674616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009800177,0.0000721066,0.0002442189,0.00003341498,0.000004599653,0.00002996417,0.0000161255,0.0001883827,0.9962877,0.0001104946,0.00003149335,0.002001422],"study_design_scores_gemma":[0.00007417687,0.002397562,0.002471908,0.00001125677,0.00002562692,0.0001329224,0.00002466085,0.001040818,0.9925795,0.00008767447,0.001148612,0.000005135552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986134,0.000304402,0.0004015507,0.00002948243,0.00002368343,0.000009033862,0.00004874739,0.00001020172,0.0005595572],"genre_scores_gemma":[0.9988686,0.0001416672,0.000293904,0.00001545907,0.000006679122,0.000004628072,0.00008091876,0.000003711745,0.0005843395],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008111046,"threshold_uncertainty_score":0.002713382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02389906791943569,"score_gpt":0.2705869970077663,"score_spread":0.2466879290883306,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}