{"id":"W2766747033","doi":"10.1002/mc.22748","title":"Novel genetic variants in the P38MAPK pathway gene <i>ZAK</i> and susceptibility to lung cancer","year":2017,"lang":"en","type":"review","venue":"Molecular Carcinogenesis","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Ontario; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Duke Cancer Institute; National Cancer Institute; Cancer Research UK; National Institutes of Health; National Institute on Drug Abuse; National Human Genome Research Institute; World Health Organization","keywords":"Single-nucleotide polymorphism; Biology; Genome-wide association study; Expression quantitative trait loci; Lung cancer; Carcinogenesis; Genetics; Gene; Locus (genetics); Genetic association; Quantitative trait locus; Oncology; Genotype; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001010054,0.0006076095,0.001285675,0.0001395063,0.0002377107,0.0000805079,0.0009831196,0.0006940971,0.00001173558],"category_scores_gemma":[0.0004079634,0.0004721562,0.0004707709,0.000212143,0.0001145105,0.000002830873,0.000494532,0.0002394542,0.00000675292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009510051,"about_ca_system_score_gemma":0.0005149458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000855654,"about_ca_topic_score_gemma":0.0009487431,"domain_scores_codex":[0.9964675,0.000663303,0.0007424582,0.001215708,0.0002420554,0.0006690134],"domain_scores_gemma":[0.9975091,0.00006684861,0.0004042774,0.001727287,0.0001136513,0.0001788643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002681118,0.0002395887,0.01573988,0.003154146,0.0007975526,0.0001310357,0.0001991843,0.0002075286,0.0423708,0.00002950729,0.0015709,0.935533],"study_design_scores_gemma":[0.0008231502,0.0002510756,0.07411349,0.0009977595,0.001506774,0.0002599602,0.00004294294,0.00005020499,0.000978702,0.00003435462,0.9192858,0.001655811],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02990974,0.9653646,0.002372095,0.0001859648,0.0002385851,0.001400278,0.0003851261,0.000007812454,0.0001357983],"genre_scores_gemma":[0.01729422,0.9778388,0.002390704,0.0008169401,0.0003143591,0.0008423869,0.0002542024,0.00009811643,0.0001502989],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9338772,"threshold_uncertainty_score":0.999773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04996301829332167,"score_gpt":0.3407927200074874,"score_spread":0.2908297017141658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}