{"id":"W2766874121","doi":"10.1038/nrmicro.2017.120","title":"Anti-CRISPR: discovery, mechanism and function","year":2017,"lang":"en","type":"review","venue":"Nature Reviews Microbiology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":409,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"CRISPR; Biology; Horizontal gene transfer; Mobile genetic elements; Archaea; Computational biology; Function (biology); Mechanism (biology); Genetics; Limiting; Genome editing; Gene; Evolutionary biology; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001341178,0.001417847,0.001594463,0.001849023,0.0002893605,0.001898644,0.001708061,0.002023092,0.003215951],"category_scores_gemma":[0.001318404,0.0004701089,0.0004250775,0.001878468,0.001400712,0.001914999,0.001143824,0.003254726,0.002157636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009156871,"about_ca_system_score_gemma":0.001636943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006171037,"about_ca_topic_score_gemma":0.001324311,"domain_scores_codex":[0.9994697,0.00006207735,0.00004798682,0.00007407578,0.0002765742,0.00006958629],"domain_scores_gemma":[0.9993411,0.0003139719,0.00008660955,0.0000313092,0.0001499732,0.00007704579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000836492,0.00004493164,0.0001506165,0.009145052,0.00005659648,0.000173969,0.00003693947,0.0003919122,0.01020051,0.01157619,0.04901819,0.9191214],"study_design_scores_gemma":[0.00001248476,0.00004095906,0.0002398743,0.001044757,0.0000486826,0.0008200556,0.00002571497,0.0001143061,0.002990874,0.003398645,0.9912422,0.00002137114],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001720796,0.9941972,0.001874468,0.0009120537,0.0008307235,0.00001062745,0.00005035002,0.00006141554,0.001890931],"genre_scores_gemma":[0.001399703,0.9944097,0.001085532,0.001044416,0.0004048233,0.00001434992,0.00009834562,0.0000102734,0.001532822],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003215951,"threshold_uncertainty_score":0.0107584,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02326605487284036,"score_gpt":0.372061683673262,"score_spread":0.3487956288004216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}