{"id":"W2766892765","doi":"10.1111/bjh.14977","title":"Autoantibodies in immune thrombocytopenia affect the physiological interaction between megakaryocytes and bone marrow extracellular matrix proteins","year":2017,"lang":"en","type":"article","venue":"British Journal of Haematology","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Hospital Foundation","funders":"Consejo Nacional de Investigaciones Científicas y Técnicas; Fondazione Cariplo","keywords":"Thrombopoiesis; Platelet; Autoantibody; Platelet membrane glycoprotein; Platelet Glycoprotein GPIb-IX Complex; Immunology; Von Willebrand factor; Bone marrow; Platelet disorder; Receptor; Immune system; Chemistry; Megakaryocyte; Biology; Cell biology; Antibody; Medicine; Internal medicine; Haematopoiesis; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002899781,0.000547935,0.0003832863,0.001061204,0.0002197857,0.0003590985,0.0001972076,0.0007473931,0.002866961],"category_scores_gemma":[0.0006766375,0.0002648742,0.0003268393,0.0005131997,0.0001920787,0.0002720161,0.0003518997,0.0004340475,0.0005433609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002021805,"about_ca_system_score_gemma":0.00007902048,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006825976,"about_ca_topic_score_gemma":0.0003537523,"domain_scores_codex":[0.9997807,0.00006626749,0.00003262113,0.00003555958,0.00004975542,0.00003512667],"domain_scores_gemma":[0.9998312,0.00005170362,0.00005824609,0.00001141089,0.00002154076,0.00002584036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004933134,0.000434622,0.390473,0.001767611,0.000787912,0.1523123,0.001209002,0.0005403488,0.2888103,0.002012194,0.007442452,0.1492771],"study_design_scores_gemma":[0.0002033303,0.001044813,0.7355573,0.0003735806,0.0007871724,0.2155391,0.0003505623,0.001161756,0.02343392,0.001875262,0.01964531,0.00002794204],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9495136,0.03605053,0.001761792,0.0005774465,0.0001232636,0.00005160918,0.000262636,0.0001311222,0.01152807],"genre_scores_gemma":[0.9952852,0.002915309,0.0003297439,0.0001918233,0.00006573465,0.0000102334,0.0001425393,0.00000936578,0.001050026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002866961,"threshold_uncertainty_score":0.009590924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02858341406291606,"score_gpt":0.3218868552851887,"score_spread":0.2933034412222727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}