{"id":"W2766991138","doi":"10.1158/2326-6066.cir-17-0229","title":"Natural Killer T-cell Immunotherapy in Combination with Chemotherapy-Induced Immunogenic Cell Death Targets Metastatic Breast Cancer","year":2017,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Beatrice Hunter Cancer Research Institute; Dalhousie University","funders":"Canadian Institutes of Health Research; Dalhousie University; Canadian Cancer Society","keywords":"Immunotherapy; Breast cancer; Medicine; Immunogenic cell death; Metastatic breast cancer; Immunology; Cancer immunotherapy; Cancer; Natural killer cell; Chemotherapy; Immune system; Cancer research; Active immunotherapy; T cell; Cytotoxic T cell; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001115349,0.0003666118,0.0005317106,0.0002476188,0.0000881024,0.0002275242,0.0001987044,0.0002044289,0.0007311215],"category_scores_gemma":[0.00008158706,0.00009518237,0.0002165977,0.0001509135,0.0001768309,0.0001522283,0.0001935253,0.0005500037,0.0002073217],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000255423,"about_ca_system_score_gemma":0.000224994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003106484,"about_ca_topic_score_gemma":0.0006293953,"domain_scores_codex":[0.9998633,0.00002948079,0.00001000112,0.00002301833,0.00003292604,0.00004129694],"domain_scores_gemma":[0.9999596,0.000005064066,0.00001009793,0.000006123736,0.000004461256,0.00001472891],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001245187,0.0007084225,0.0004018065,0.0001139363,0.00002480434,0.00009954054,0.00002018778,0.0006769727,0.9791511,0.0001516025,0.0002167896,0.0171895],"study_design_scores_gemma":[0.0007318711,0.01237233,0.005285431,0.00002200268,0.0001212711,0.0008233071,0.00002856033,0.003603378,0.9689687,0.0001756236,0.007856235,0.00001129853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945866,0.002373004,0.001296289,0.0001402212,0.00009060753,0.0001212014,0.00008774515,0.00007484827,0.001229563],"genre_scores_gemma":[0.9962425,0.001220349,0.001119174,0.00003903999,0.00003833625,0.00008697604,0.0001343301,0.000006945225,0.00111233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007311215,"threshold_uncertainty_score":0.002445817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0376868690230746,"score_gpt":0.3424158288692887,"score_spread":0.3047289598462141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}