{"id":"W2766991138","doi":"10.1158/2326-6066.cir-17-0229","title":"Natural Killer T-cell Immunotherapy in Combination with Chemotherapy-Induced Immunogenic Cell Death Targets Metastatic Breast Cancer","year":2017,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Beatrice Hunter Cancer Research Institute; Dalhousie University","funders":"Canadian Institutes of Health Research; Dalhousie University; Canadian Cancer Society","keywords":"Immunotherapy; Breast cancer; Medicine; Immunogenic cell death; Metastatic breast cancer; Immunology; Cancer immunotherapy; Cancer; Natural killer cell; Chemotherapy; Immune system; Cancer research; Active immunotherapy; T cell; Cytotoxic T cell; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009336401,0.0004518751,0.0006354011,0.0006207536,0.001408044,0.0001613103,0.001157501,0.000407086,0.004932173],"category_scores_gemma":[0.00003930708,0.000378188,0.0001605607,0.0003278235,0.0007147331,0.0006389677,0.0002125766,0.002287511,0.0005721507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008069574,"about_ca_system_score_gemma":0.0005663047,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008313961,"about_ca_topic_score_gemma":0.0005179202,"domain_scores_codex":[0.996421,0.0008191101,0.0005547449,0.0007743243,0.000191956,0.00123881],"domain_scores_gemma":[0.9974965,0.0002046071,0.0004220309,0.001244672,0.000596375,0.00003581243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00499865,0.0007692118,0.01142363,0.00004187883,0.0005959976,0.00001741057,0.0008793448,0.000008087172,0.9644066,0.0001311137,0.002686931,0.01404117],"study_design_scores_gemma":[0.02208768,0.001096501,0.3260252,0.000236342,0.00005789357,0.0001762109,0.001116794,0.00006913192,0.6087955,0.0001349665,0.03937513,0.0008286192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9492743,0.03701974,0.00002450537,0.00339435,0.0065292,0.001043371,0.00001536681,0.0000821686,0.002616982],"genre_scores_gemma":[0.9579575,0.007427241,0.00003102465,0.0002546847,0.00005394553,0.0006726126,0.00009045454,0.00008894713,0.03342357],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.355611,"threshold_uncertainty_score":0.999892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0376868690230746,"score_gpt":0.3424158288692887,"score_spread":0.3047289598462141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}