{"id":"W2767024445","doi":"10.1016/j.molimm.2017.10.016","title":"Surfactant protein D regulates caspase-8-mediated cascade of the intrinsic pathway of apoptosis while promoting bleb formation","year":2017,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; University of Toronto; Hospital for Sick Children","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Cystic Fibrosis Canada","keywords":"Cytochrome c; Apoptosome; Intrinsic apoptosis; Cell biology; Apoptosis; Caspase-9; Caspase; Bleb (medicine); Caspase 3; Biology; Signal transduction; Chemistry; Mitochondrion; Molecular biology; Biochemistry; Programmed cell death","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003146056,0.0003399774,0.0003149249,0.0004393815,0.000344207,0.0004362726,0.0002613475,0.0004042269,0.00250762],"category_scores_gemma":[0.000356182,0.0001826163,0.0004268271,0.0001299981,0.0003923231,0.0005056226,0.000414928,0.0009653719,0.0006648774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006621194,"about_ca_system_score_gemma":0.0004716685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000666019,"about_ca_topic_score_gemma":0.000781814,"domain_scores_codex":[0.9996002,0.00008494246,0.00003931595,0.00006623336,0.0000751953,0.0001340892],"domain_scores_gemma":[0.9997094,0.00002857841,0.00007286807,0.00003421882,0.00006592788,0.00008897595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005904633,0.00006100162,0.0009065075,0.00008027571,0.00001279413,0.0001296966,0.00003155696,0.00003975319,0.9949428,0.0004898524,0.0001600856,0.002555158],"study_design_scores_gemma":[0.0000919384,0.0002713203,0.01539001,0.000017624,0.00003155953,0.0004588542,0.0001062721,0.001039706,0.9786506,0.0003534589,0.003580294,0.000008398294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9812074,0.006558084,0.007530592,0.0006383799,0.0001468713,0.00006114205,0.0003752679,0.0001851594,0.003297148],"genre_scores_gemma":[0.9935702,0.00120307,0.001562384,0.00007982889,0.00002368914,0.00003226929,0.0003385658,0.0000162605,0.003173724],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00250762,"threshold_uncertainty_score":0.008388877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02653573817808811,"score_gpt":0.2945573200438348,"score_spread":0.2680215818657467,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}