{"id":"W2767124649","doi":"10.1093/carcin/bgx125","title":"TPD52L2 impacts proliferation, invasiveness and apoptosis of glioblastoma cells via modulation of wnt/β-catenin/snail signaling","year":2017,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation","funders":"Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"U87; Temozolomide; Cancer research; Wnt signaling pathway; Cell culture; Downregulation and upregulation; Glioma; Cell growth; Apoptosis; clone (Java method); Cell; Snail; Biology; SNAI1; Medicine; Signal transduction; Cancer; Internal medicine; Cell biology; Epithelial–mesenchymal transition; Metastasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000861369,0.0002347599,0.0001821631,0.0001752673,0.0001317854,0.0002100635,0.0001004812,0.0001826558,0.0009023289],"category_scores_gemma":[0.00007607882,0.00008224,0.0001688616,0.0001430877,0.0001530756,0.0001202736,0.0001062086,0.0002201365,0.0002036471],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002490724,"about_ca_system_score_gemma":0.000147091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008527157,"about_ca_topic_score_gemma":0.001776333,"domain_scores_codex":[0.9999017,0.0000120682,0.00001251521,0.00002081013,0.00002695585,0.00002602532],"domain_scores_gemma":[0.999964,0.000003386555,0.00001135208,0.000003283038,0.000004395043,0.00001361364],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001936084,0.00003112021,0.001219947,0.00005108098,0.000008141001,0.0001018384,0.000009164187,0.0001052263,0.9966259,0.00006710838,0.0001510405,0.001435718],"study_design_scores_gemma":[0.00006902376,0.0007198634,0.03033529,0.00001558547,0.00007578926,0.0009077655,0.00008106418,0.003930612,0.9589401,0.000056237,0.004856887,0.0000117237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958936,0.001261833,0.0008122166,0.00009482258,0.0000243949,0.00001289688,0.0006251184,0.00006083672,0.001214394],"genre_scores_gemma":[0.9976179,0.0004125112,0.0003482212,0.00004586458,0.000003556157,0.00001796847,0.0004973217,0.000006428275,0.00105019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009023289,"threshold_uncertainty_score":0.003018558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02164433378682972,"score_gpt":0.260361746704851,"score_spread":0.2387174129180213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}