{"id":"W2767124649","doi":"10.1093/carcin/bgx125","title":"TPD52L2 impacts proliferation, invasiveness and apoptosis of glioblastoma cells via modulation of wnt/β-catenin/snail signaling","year":2017,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation","funders":"Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"U87; Temozolomide; Cancer research; Wnt signaling pathway; Cell culture; Downregulation and upregulation; Glioma; Cell growth; Apoptosis; clone (Java method); Cell; Snail; Biology; SNAI1; Medicine; Signal transduction; Cancer; Internal medicine; Cell biology; Epithelial–mesenchymal transition; Metastasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001485332,0.0001771865,0.0004537423,0.0001644777,0.0001710513,0.00002841134,0.00009335415,0.0001000235,0.00002321939],"category_scores_gemma":[0.00009095018,0.0001505741,0.0001180444,0.00009145622,0.0001157777,0.0001433834,0.00005607471,0.00003651076,0.000003323298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004490156,"about_ca_system_score_gemma":0.00007846763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002600087,"about_ca_topic_score_gemma":0.00002746352,"domain_scores_codex":[0.9989007,0.00003559596,0.0003632813,0.0002620754,0.0002568789,0.0001815],"domain_scores_gemma":[0.9986203,0.00006225634,0.0003900919,0.0003991164,0.0003835544,0.0001446729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001253796,0.0001421531,0.3537238,0.0002076166,0.0001021077,0.000006082938,0.0002065002,0.0001232751,0.6434641,0.00002178857,0.00001236172,0.001864738],"study_design_scores_gemma":[0.001019378,0.0002468957,0.3610362,0.0001250986,0.0001868424,0.000009801706,0.00003210487,0.0003602903,0.6368677,0.00003863833,0.000002186659,0.00007478761],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998513,0.0005286129,0.0001279623,0.0001979334,0.00008359078,0.0004717015,0.00001770149,0.00001361447,0.0000458474],"genre_scores_gemma":[0.9993934,0.0001360347,0.0002890781,0.00002309034,0.00006563957,0.00004229651,0.00001395247,0.00002497364,0.00001154906],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007312418,"threshold_uncertainty_score":0.6140234,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02164433378682972,"score_gpt":0.260361746704851,"score_spread":0.2387174129180213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}