{"id":"W2767298835","doi":"10.1242/dev.152504","title":"The long non-coding RNA <i>ROCR</i> contributes to SOX9 expression and chondrogenic differentiation of human mesenchymal stem cells","year":2017,"lang":"en","type":"article","venue":"Development","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Medical Research Council Canada; Versus Arthritis; JGW Patterson Foundation; Arthritis Research UK; Instituto de Salud Carlos III; National Institute for Health and Care Research; NIHR Newcastle Biomedical Research Centre; Newcastle upon Tyne Hospitals NHS Foundation Trust","keywords":"Chondrocyte; Chondrogenesis; Biology; SOX9; Mesenchymal stem cell; Cell biology; Cellular differentiation; Transcription factor; Cartilage; RNA interference; Stem cell; RNA; Gene expression; Gene; Genetics; Anatomy","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002477669,0.0001210657,0.0001261354,0.00003840313,0.0006552568,0.0001021821,0.0003094203,0.00009762937,0.000003974432],"category_scores_gemma":[0.00002611278,0.00009574868,0.00003964848,0.000030106,0.00005190253,0.000004771528,0.0004748123,0.00007991082,0.000003703927],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003652601,"about_ca_system_score_gemma":0.0000888151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000923371,"about_ca_topic_score_gemma":0.00006461806,"domain_scores_codex":[0.9990234,0.00003268084,0.0002168079,0.0002708435,0.0002081965,0.0002480634],"domain_scores_gemma":[0.9992725,0.00001067732,0.0001319074,0.000396995,0.0001066452,0.00008125018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003932758,0.00001494474,0.0001962671,0.00001882533,0.00005245773,0.000001585856,0.00009094657,0.000005829534,0.9924205,0.00003026466,0.0003487355,0.00678035],"study_design_scores_gemma":[0.0005127577,0.00005871569,0.006010927,0.00006668113,0.000007777697,0.000001253404,0.00004336239,0.00002499857,0.9906921,0.00001561015,0.002454894,0.0001109554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9712786,0.0003874511,0.02749083,0.0001129073,0.0001752456,0.000376215,0.000004531287,0.000004589594,0.0001696508],"genre_scores_gemma":[0.9986396,0.0001429632,0.0002817381,0.0000316986,0.00003427763,0.00005255156,0.00001807102,0.00001550387,0.0007835298],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02736108,"threshold_uncertainty_score":0.5039772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01241299919846659,"score_gpt":0.2688845586528464,"score_spread":0.2564715594543798,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}