{"id":"W2767327745","doi":"10.1016/j.jid.2017.10.028","title":"Role of Dysregulated Cytokine Signaling and Bacterial Triggers in the Pathogenesis of Cutaneous T-Cell Lymphoma","year":2017,"lang":"en","type":"article","venue":"Journal of Investigative Dermatology","topic":"Cutaneous lymphoproliferative disorders research","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Office of Research Infrastructure Programs, National Institutes of Health; National Institute of Dental and Craniofacial Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; Hearst Foundations; National Cancer Institute; National Institute of General Medical Sciences; School of Medicine, New York University; National Institutes of Health; Kræftens Bekæmpelse; York University; Cutaneous Lymphoma Foundation; Novo Nordisk Fonden; Patton Charitable Foundation; Concern Foundation","keywords":"Biology; Lymphoma; Cutaneous T-cell lymphoma; Transcriptome; Mycosis fungoides; Cytokine; Cancer research; Pathogenesis; Malignancy; T-cell receptor; T cell; Immunology; Disease; Immune system; Medicine; Gene; Pathology; Genetics; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003388578,0.0004192491,0.0003296445,0.0006547468,0.0003098241,0.001277774,0.0002448808,0.0005615877,0.001083919],"category_scores_gemma":[0.0004573942,0.0001784157,0.0001667687,0.0003073818,0.0004582856,0.0005973823,0.0005221447,0.0006632743,0.0003654808],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004691073,"about_ca_system_score_gemma":0.0003238836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001867744,"about_ca_topic_score_gemma":0.0002079364,"domain_scores_codex":[0.9995403,0.000129417,0.00004740407,0.00004964967,0.00009577364,0.0001373828],"domain_scores_gemma":[0.999751,0.0000375492,0.00009610733,0.00002530883,0.00003569389,0.00005436313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002808603,0.0005480782,0.09641584,0.000674477,0.0001344679,0.01320222,0.0003615321,0.001176919,0.8206554,0.005102626,0.001757937,0.05716195],"study_design_scores_gemma":[0.0004737268,0.002176976,0.5493287,0.0004318118,0.0005827389,0.03540146,0.002506772,0.01517153,0.3495696,0.0102699,0.03400121,0.00008559374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9612262,0.03217671,0.001451376,0.00050293,0.0001463184,0.00004075478,0.0001445572,0.00007417359,0.004236807],"genre_scores_gemma":[0.9951718,0.003399519,0.0005775839,0.0000937444,0.00009430303,0.00001716245,0.00005913316,0.000006328299,0.0005803424],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001277774,"threshold_uncertainty_score":0.003626049,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02060224989237652,"score_gpt":0.2803426674434915,"score_spread":0.259740417551115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}