{"id":"W2767387519","doi":"10.1093/neuonc/nox168.041","title":"ACTR-50. CLINICAL TRIALS WITH DIANHYDROGALACTITOL (VAL-083) IN MGMT-UNMETHYLATED GLIOBLASTOMA","year":2017,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Delmar (Canada)","funders":"","keywords":"Temozolomide; Cancer research; DNA repair; Methyltransferase; Medicine; Cancer; Bevacizumab; Radiation therapy; Glioma; Oncology; Internal medicine; Biology; Chemotherapy; DNA; Genetics; Methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009761745,0.0008018498,0.0009535077,0.0005214894,0.000293877,0.000697309,0.0007017329,0.0009887593,0.003605985],"category_scores_gemma":[0.0003887687,0.0002362833,0.0007780456,0.0004823435,0.0003266244,0.0004539409,0.0003303435,0.00202509,0.001036898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004588571,"about_ca_system_score_gemma":0.0006219922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001064374,"about_ca_topic_score_gemma":0.004496401,"domain_scores_codex":[0.9997305,0.0001338548,0.00002437693,0.00002433092,0.00003636178,0.00005050202],"domain_scores_gemma":[0.9998046,0.00003507321,0.00004083008,0.0000151391,0.00001862835,0.00008583531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.09002119,0.01712051,0.002385641,0.005166881,0.001499427,0.0006976746,0.0004002898,0.003363841,0.1540104,0.002210862,0.02804154,0.6950817],"study_design_scores_gemma":[0.1704819,0.5647114,0.02930258,0.001214259,0.002069317,0.00228708,0.0002091756,0.003216876,0.04000513,0.002067987,0.1842798,0.0001545344],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7958708,0.1471708,0.003552753,0.005685274,0.00127311,0.005239201,0.005180763,0.001500286,0.03452702],"genre_scores_gemma":[0.8523355,0.09292051,0.007057649,0.008995993,0.0006097698,0.004727296,0.01074068,0.0001896421,0.02242304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003605985,"threshold_uncertainty_score":0.01206326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09585768033336821,"score_gpt":0.439147125699677,"score_spread":0.3432894453663088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}