{"id":"W2767408431","doi":"10.1016/j.neuint.2017.11.004","title":"Mechanisms of RhoA inactivation and CDC42 and Rac1 activation during zebrafish optic nerve regeneration","year":2017,"lang":"en","type":"article","venue":"Neurochemistry International","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institute for Theoretical Astrophysics","keywords":"RHOA; Zebrafish; Regeneration (biology); Cell biology; RAC1; Wnt signaling pathway; Biology; Axon; CDC42; Optic nerve; Neuroscience; Signal transduction; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007994933,0.0001259503,0.0001107022,0.00005596549,0.0003662768,0.0001895893,0.0002034916,0.00008273862,0.00002888753],"category_scores_gemma":[0.0007171138,0.0001257655,0.00002854201,0.00003363472,0.0001094271,0.0007362323,0.0001164739,0.0001242869,0.000001074874],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003383871,"about_ca_system_score_gemma":0.00001909963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000974018,"about_ca_topic_score_gemma":0.000001423461,"domain_scores_codex":[0.9990151,0.00003022306,0.0002252453,0.0003567997,0.0002726283,0.0001000087],"domain_scores_gemma":[0.9992102,0.00005858114,0.0003587727,0.0002311301,0.00009394305,0.00004741195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006193578,0.00003333507,0.0002053863,0.00003364695,0.000005050743,0.00000577226,0.00004799229,0.00004424282,0.9932348,0.005817044,0.00001345856,0.0004973841],"study_design_scores_gemma":[0.000462339,0.00003022431,0.01099055,0.00003694426,0.00000658467,0.00006392806,0.0000212429,0.00313366,0.9832882,0.001841522,0.00001767385,0.0001071286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956313,0.000003492823,0.00148073,0.001154054,0.0002886095,0.0001029425,0.0000140946,0.00002631946,0.001298476],"genre_scores_gemma":[0.9988179,0.00001841113,0.0003099363,0.00005214537,0.00016589,0.00001431015,0.00002086461,0.00001224779,0.0005882722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01078516,"threshold_uncertainty_score":0.5128567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01906708602542904,"score_gpt":0.26493769962492,"score_spread":0.245870613599491,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}