{"id":"W2767415052","doi":"10.1097/qad.0000000000001685","title":"Concomitant medication polypharmacy, interactions and imperfect adherence are common in Australian adults on suppressive antiretroviral therapy","year":2017,"lang":"en","type":"article","venue":"AIDS","topic":"HIV-related health complications and treatments","field":"Medicine","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Ottawa Mental Health Centre","funders":"Fiona Stanley Hospital; National Health and Medical Research Council; Balnaves Foundation; Department of Health, State Government of Victoria; Australian Government; Gilead Sciences; Bristol-Myers Squibb; ViiV Healthcare; Government of Western Australia; U.S. Department of Health and Human Services","keywords":"Polypharmacy; Concomitant; Medicine; Pharmacodynamics; Adverse effect; Comorbidity; Internal medicine; Pharmacokinetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001862298,0.0001933772,0.0004409195,0.0006882584,0.0005613706,0.0006981808,0.0004190511,0.0004585443,0.0009555448],"category_scores_gemma":[0.006853024,0.0002726621,0.0004413745,0.001307631,0.0002830302,0.0004753558,0.0007487455,0.0006445905,0.00009740885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005635913,"about_ca_system_score_gemma":0.0006744315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03582522,"about_ca_topic_score_gemma":0.04698669,"domain_scores_codex":[0.9979014,0.0006897335,0.0003433318,0.000196862,0.0007395782,0.0001290282],"domain_scores_gemma":[0.995566,0.0004949903,0.003029981,0.000150158,0.0004842507,0.000274595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00002612062,0.00004188674,0.9939128,0.00007436738,0.00007355806,0.0000562526,0.0004563307,0.00003414106,0.0001395867,0.00001803453,0.00008477428,0.005082353],"study_design_scores_gemma":[0.000001258086,0.00003756621,0.9994602,0.00001761455,0.00001559081,0.00009211866,0.0001328539,0.00009850088,0.00001318274,0.00001023157,0.0001193558,0.000001594338],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978237,0.0008973139,0.0001213733,0.0001817684,0.000004911675,0.00003222745,0.0001981096,0.000002597006,0.0007379202],"genre_scores_gemma":[0.9990044,0.0004125437,0.0002616155,0.00006486983,0.000008151127,0.00001643548,0.00009259249,5.612393e-7,0.0001388751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03582522,"threshold_uncertainty_score":0.07123339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03985618479934169,"score_gpt":0.3858440716949917,"score_spread":0.34598788689565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}