{"id":"W2767581051","doi":"10.1093/neuonc/nox168.1089","title":"SCDT-06. QUANTIFIABLE LEVELS OF THE TRANSGENE, CYTOSINE DEAMINASE, IN TUMOR SAMPLES FOLLOWING INTRAVENOUS DELIVERY OF TOCA 511 IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA","year":2017,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Brain Institute","funders":"","keywords":"Cytosine deaminase; Molecular biology; Glioma; Immunohistochemistry; Biology; Genetic enhancement; Pathology; Cancer research; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001214475,0.0001513369,0.000257453,0.0002424075,0.0001050679,0.000251853,0.00007981711,0.0002119339,0.0006089787],"category_scores_gemma":[0.0002202757,0.00009681157,0.00007941102,0.0001812055,0.0001187123,0.0001034524,0.00005507845,0.0002832102,0.0001547764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003074657,"about_ca_system_score_gemma":0.0001488846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008553817,"about_ca_topic_score_gemma":0.00141584,"domain_scores_codex":[0.9999338,0.00001042444,0.000003863426,0.00002005205,0.00001855422,0.00001332674],"domain_scores_gemma":[0.9999021,0.0000197231,0.00002705081,0.000006534129,0.00001421843,0.00003038691],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0114097,0.0005214351,0.1118738,0.0001518895,0.00006405041,0.002379196,0.0002661214,0.0005491597,0.8263327,0.00008268379,0.0006438415,0.04572539],"study_design_scores_gemma":[0.0006464918,0.02598821,0.5794353,0.0000215241,0.0002385583,0.009816432,0.0002080832,0.005114525,0.3746422,0.00008587304,0.003778056,0.00002474257],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984029,0.0004051668,0.0003419081,0.00002163955,0.000003552844,0.00002888399,0.0001962037,0.0000314247,0.000568354],"genre_scores_gemma":[0.9987684,0.00008138068,0.0003566542,0.00002620808,0.000002639922,0.00001642237,0.0003064531,0.000006499378,0.0004353949],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008553817,"threshold_uncertainty_score":0.002230883,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03189538344428734,"score_gpt":0.2989544667792111,"score_spread":0.2670590833349238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}