{"id":"W2767587783","doi":"10.1089/ars.2017.7082","title":"Acetylation Regulates Thioredoxin Reductase Oligomerization and Activity","year":2017,"lang":"en","type":"article","venue":"Antioxidants and Redox Signaling","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Cancer Society Research Institute; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Thioredoxin reductase; Acetylation; Thioredoxin; Cell biology; Chemistry; Biochemistry; Reductase; Enzyme; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001815567,0.0002060035,0.0001955055,0.0001331915,0.0001899379,0.0004298163,0.0002214134,0.0002343744,0.001718578],"category_scores_gemma":[0.0001778598,0.0001606873,0.0002851461,0.0001201221,0.0001878916,0.0002588703,0.0001768744,0.000420557,0.0006965635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000274795,"about_ca_system_score_gemma":0.0001377008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005434694,"about_ca_topic_score_gemma":0.0006462627,"domain_scores_codex":[0.9998524,0.00002237385,0.00001122381,0.00005319572,0.00002622072,0.00003452475],"domain_scores_gemma":[0.9998522,0.00001396692,0.00005539133,0.00001465615,0.00003365134,0.00003012292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000134518,0.00002461768,0.001339665,0.00001634781,0.000006868514,0.00002238226,0.00001774207,0.00003077359,0.9968877,0.00007055817,0.00005270485,0.001395994],"study_design_scores_gemma":[0.00002557419,0.0003028774,0.06071832,0.000008460249,0.00003188264,0.0003179032,0.0000629064,0.001456124,0.9343844,0.0001467229,0.002533193,0.0000115361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940478,0.002392053,0.002257495,0.0001167238,0.00003321637,0.000009591618,0.0001290847,0.00007690566,0.0009372468],"genre_scores_gemma":[0.9968777,0.0005195087,0.0009191583,0.00003661422,0.00000903163,0.000005666178,0.00020339,0.00001564977,0.0014133],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001718578,"threshold_uncertainty_score":0.005749226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01131914388995771,"score_gpt":0.2724962310567807,"score_spread":0.261177087166823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}