{"id":"W2767696368","doi":"10.1016/j.thromres.2017.11.003","title":"Over-expression of cyclooxygenase-2 in increased reticulated platelets leads to aspirin resistance after elective off-pump coronary artery bypass surgery","year":2017,"lang":"en","type":"article","venue":"Thrombosis Research","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Government of Jiangsu Province; Hamilton Health Sciences","keywords":"Aspirin; Medicine; Platelet; Cyclooxygenase; Platelet activation; Arachidonic acid; Artery; Mean platelet volume; Internal medicine; Anesthesia; Coronary artery bypass surgery; Gastroenterology; Cardiology; Surgery; Enzyme; Chemistry; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00301083,0.0002844068,0.000891613,0.0007290803,0.0002813146,0.00005952259,0.0003465302,0.0003123166,0.0002665243],"category_scores_gemma":[0.001859798,0.0002495931,0.0001637336,0.0004776465,0.0003532528,0.0002651441,0.000287263,0.0007954146,0.0001266717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003654172,"about_ca_system_score_gemma":0.0004381096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004433046,"about_ca_topic_score_gemma":0.0006749096,"domain_scores_codex":[0.995786,0.0006730998,0.0006060129,0.0006427221,0.001355024,0.000937165],"domain_scores_gemma":[0.9966365,0.0009196372,0.0001825967,0.001364395,0.0004570038,0.0004399274],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004689737,0.0003269897,0.4273337,0.0003981989,0.00005912285,0.0009939645,0.0003666963,0.000002300813,0.560897,0.00001188661,0.004329079,0.0005913725],"study_design_scores_gemma":[0.001191924,0.0002482061,0.7187011,0.001684419,0.00001677695,0.000007750899,0.00002487346,0.00005089211,0.2775107,0.00003074963,0.0003523316,0.0001802302],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970248,0.0003033676,0.000001884133,0.0004409892,0.000149646,0.0009198946,0.00002880757,0.00003987105,0.001090697],"genre_scores_gemma":[0.9987806,0.0001632316,0.00006191856,0.0001148226,0.0001677814,0.000234128,0.00002716826,0.00006325225,0.0003870868],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2913675,"threshold_uncertainty_score":0.9999956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04917186665705782,"score_gpt":0.3673410539159386,"score_spread":0.3181691872588808,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}