{"id":"W2767699464","doi":"10.1093/neuonc/nox168.462","title":"IMMU-03. THERAPEUTIC TARGETING OF TUMORIGENIC EphA2+/EphA3+ BRAIN TUMOR INITIATING CELLS WITH BISPECIFIC ANTIBODY IN HUMAN GLIOBLASTOMA","year":2017,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McMaster University","funders":"","keywords":"EPH receptor A2; Cancer research; Population; Gene knockdown; Receptor tyrosine kinase; Protein kinase B; Biology; Medicine; Receptor; Cell culture; Phosphorylation; Internal medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003170687,0.0006117402,0.0004498554,0.0004454863,0.0001678674,0.0003695851,0.0004069232,0.0005852839,0.001447484],"category_scores_gemma":[0.00009657065,0.0001796292,0.0004324433,0.000314993,0.0001839469,0.0001452976,0.0002317366,0.0008692548,0.0008755295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004550515,"about_ca_system_score_gemma":0.0005854311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001747713,"about_ca_topic_score_gemma":0.002386049,"domain_scores_codex":[0.9998516,0.00003149793,0.000008167459,0.00002414762,0.00003268576,0.0000519063],"domain_scores_gemma":[0.9999657,0.000005716744,0.000004966892,0.000005170108,0.000005724218,0.00001268394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001200491,0.001322713,0.000519489,0.000231729,0.0000648195,0.0002628278,0.00006478062,0.0007620807,0.9724939,0.0009871152,0.001277896,0.02081213],"study_design_scores_gemma":[0.0003899945,0.004543403,0.00385337,0.00001965233,0.00009303889,0.0006447183,0.00002480437,0.004374493,0.9750553,0.0001355611,0.01085664,0.000009162097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9734841,0.004905261,0.006972134,0.0004055247,0.0001817019,0.0005034372,0.001338281,0.0008077022,0.01140178],"genre_scores_gemma":[0.9719338,0.003388132,0.01149497,0.0003280695,0.00003763433,0.0006884204,0.003667799,0.00007945531,0.008381668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001747713,"threshold_uncertainty_score":0.004842341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03993740797815651,"score_gpt":0.3378708080221566,"score_spread":0.297933400044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}