{"id":"W2767747918","doi":"10.1093/neuonc/nox168.254","title":"DDIS-19. NOVEL PEPTIDE HOMING TO GLIOMA-SPECIFIC ISOFORM OF BREVICAN SELECTIVELY TARGETS MALIGNANT BRAIN TUMORS","year":2017,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Glioma; Gene isoform; Peptide library; Peptide; Biology; B cell; Cancer research; Molecular biology; Chemistry; Biochemistry; Peptide sequence; Antibody; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001172968,0.0005006228,0.0003191026,0.0003104142,0.0001369351,0.0003295684,0.0003757587,0.0003672197,0.001163475],"category_scores_gemma":[0.00009664176,0.0001661262,0.0002280229,0.0002166388,0.0001676906,0.000192908,0.0002800489,0.0005819091,0.0006651801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005109349,"about_ca_system_score_gemma":0.0002894982,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004132292,"about_ca_topic_score_gemma":0.0006272155,"domain_scores_codex":[0.9998783,0.00001260968,0.0000099082,0.00002903447,0.00003789127,0.00003221635],"domain_scores_gemma":[0.9999657,0.000003897075,0.000008746847,0.000002932625,0.00000472633,0.00001399861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001490731,0.0000839057,0.0001560587,0.0001013927,0.000009613119,0.0000981835,0.00001245742,0.0002607726,0.9881288,0.0003224829,0.0004986307,0.01017843],"study_design_scores_gemma":[0.00005800128,0.0005257371,0.0008579119,0.000006505949,0.0000150884,0.0004252245,0.000006943364,0.001013367,0.9841411,0.00006938304,0.01287348,0.00000722763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9478403,0.009807498,0.02295085,0.0005401787,0.0002424188,0.0005544004,0.00213899,0.0007718349,0.0151535],"genre_scores_gemma":[0.9500698,0.006289235,0.02204287,0.0005363117,0.00006284352,0.0004633227,0.004921083,0.0000733569,0.0155412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001163475,"threshold_uncertainty_score":0.003892243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02755294174015084,"score_gpt":0.2926362526254673,"score_spread":0.2650833108853165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}