{"id":"W2767922176","doi":"10.3390/ht6040017","title":"Application of High-Throughput Assays to Examine Phospho-Modulation of the Late Steps of Regulated Exocytosis","year":2017,"lang":"en","type":"article","venue":"High-Throughput","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"National Health and Medical Research Council; China Scholarship Council","keywords":"Exocytosis; Throughput; Modulation (music); Cell biology; Chemistry; Biology; Computational biology; Computer science; Biochemistry; Physics; Telecommunications; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002859315,0.0002155135,0.0003715619,0.00004508477,0.0001523997,0.00001314912,0.0005195791,0.0002711467,0.00002678973],"category_scores_gemma":[0.00005516471,0.0001840918,0.0001750812,0.0001490477,0.0002323346,0.00001865507,0.0001655089,0.00008555064,0.000004800302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002507386,"about_ca_system_score_gemma":0.00005325877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001826858,"about_ca_topic_score_gemma":0.0004654366,"domain_scores_codex":[0.998421,0.00005878631,0.0005804158,0.0004032318,0.0003223168,0.0002142725],"domain_scores_gemma":[0.9974217,0.00001468591,0.0007113862,0.001544535,0.0002497216,0.00005796393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001822552,0.0001225399,0.0135818,0.00008318831,0.00008047796,2.712438e-7,0.000146459,0.001276775,0.9807494,0.001228137,0.00007009063,0.002478604],"study_design_scores_gemma":[0.0006498784,0.0001793793,0.3379669,0.00004351379,0.00006212449,8.70004e-7,0.00001475121,0.0002588026,0.6573799,0.0003839355,0.00291584,0.0001441292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.955755,0.0001484833,0.04264291,0.0002736671,0.0002517789,0.0005315443,0.00009226584,0.00001201329,0.0002923187],"genre_scores_gemma":[0.9969789,0.000154507,0.001280858,0.00003267131,0.0001126528,0.00002686986,0.0008566306,0.00003475158,0.0005221553],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.324385,"threshold_uncertainty_score":0.7507045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009749884551476164,"score_gpt":0.2293728473689154,"score_spread":0.2196229628174393,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}