{"id":"W2767936334","doi":"10.1261/rna.064618.117","title":"HIV-1 NC-induced stress granule assembly and translation arrest are inhibited by the dsRNA binding protein Staufen1","year":2017,"lang":"en","type":"article","venue":"RNA","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research; International AIDS Society","keywords":"Biology; Stress granule; RNA silencing; Cell biology; RNA-binding protein; Human immunodeficiency virus (HIV); Binding protein; Translation (biology); Virology; RNA; Genetics; RNA interference; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008390598,0.0002379727,0.0001812836,0.0001399313,0.0001661311,0.000255501,0.0001743733,0.0001820042,0.000718077],"category_scores_gemma":[0.0001200545,0.00009216564,0.0001547737,0.0001017799,0.0001745212,0.0001427702,0.000135932,0.0003362954,0.0002448738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004125373,"about_ca_system_score_gemma":0.000199465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007677685,"about_ca_topic_score_gemma":0.001159118,"domain_scores_codex":[0.9999311,0.00001335513,0.000007736744,0.00001456142,0.00001700196,0.00001618793],"domain_scores_gemma":[0.9999273,0.00001774123,0.00002377637,0.00001074825,0.000006969995,0.00001361233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005556919,0.0000140635,0.00005661604,0.00001790209,0.000001912193,0.00001917936,0.000006380229,0.00004684217,0.9990531,0.0001162285,0.00003150766,0.0005806485],"study_design_scores_gemma":[0.000007720345,0.00005979214,0.002317647,0.00000271278,0.000003362444,0.00007367188,0.000006605917,0.001210868,0.9945626,0.00003965577,0.001712712,0.000002742332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951621,0.001540885,0.001516044,0.00009864226,0.00001833007,0.00001828484,0.0002737654,0.00007851519,0.00129342],"genre_scores_gemma":[0.996463,0.0005774751,0.001108398,0.00002246321,0.000006511817,0.00002262605,0.0004117595,0.00001422428,0.001373541],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007677685,"threshold_uncertainty_score":0.002993166,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01932845220177853,"score_gpt":0.2628483421668685,"score_spread":0.24351988996509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}