{"id":"W2767995711","doi":"10.1093/annonc/mdx436.015","title":"Clinical trials and risk-based approach: reality or Utopia?","year":2017,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Ethics in Clinical Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Medicine; Quarter (Canadian coin); Clinical trial; Data collection; Medical emergency; Statistics; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.3868656,0.001766653,0.005874552,0.004260902,0.008303617,0.03131402,0.008428992,0.0378208,0.009190936],"category_scores_gemma":[0.4348457,0.001623121,0.002066382,0.002945173,0.1098009,0.05830546,0.0140475,0.06050198,0.001866975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01613151,"about_ca_system_score_gemma":0.0290729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005744767,"about_ca_topic_score_gemma":0.006178196,"domain_scores_codex":[0.7313808,0.212767,0.01059573,0.01123789,0.02962988,0.00438873],"domain_scores_gemma":[0.3766545,0.5385051,0.01622792,0.02337768,0.03155434,0.01368044],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001099957,0.0001012842,0.0007077256,0.0006333842,0.0001930991,0.0001133355,0.002131289,0.000484168,0.0001059592,0.9249151,0.04852005,0.02198456],"study_design_scores_gemma":[0.0002485877,0.00007033846,0.0003532113,0.001504617,0.00007533481,0.0001493081,0.001518907,0.0009026389,0.00009002675,0.9493336,0.04566352,0.00008981537],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0007377191,0.01372344,0.008218388,0.9672244,0.003371282,0.00002792074,0.00003169085,0.00003424103,0.006630869],"genre_scores_gemma":[0.187875,0.02138426,0.03266732,0.7108033,0.042937,0.0005429107,0.0000860327,0.0002352132,0.003468985],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.6131344,"threshold_uncertainty_score":0.7561039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.9618667575287084,"score_gpt":0.7822164604037476,"score_spread":0.1796502971249608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}