{"id":"W2768049553","doi":"10.1101/215160","title":"The Function of the COPII Gene Paralogs SEC23A and SEC23B Are Interchangeable <i>In Vivo</i>","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Sinai Health System; Lunenfeld-Tanenbaum Research Institute","funders":"National Institutes of Health; University of Michigan; American Society of Hematology","keywords":"COPII; Biology; Gene; Complementation; Genetics; Phenotype; COPI; Vesicular Transport Proteins; Zebrafish; Cell biology; Haploinsufficiency; Endoplasmic reticulum; Golgi apparatus; Secretory pathway; Peptide sequence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004198648,0.0007494757,0.0004540919,0.0005490133,0.0005472082,0.0008520546,0.0007568172,0.0006171798,0.002243074],"category_scores_gemma":[0.0003302251,0.0004594158,0.0005197577,0.0003625759,0.0009175906,0.0004057494,0.001149833,0.001426187,0.002444108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005509214,"about_ca_system_score_gemma":0.0004296784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007088694,"about_ca_topic_score_gemma":0.000739833,"domain_scores_codex":[0.9994391,0.0000935834,0.00007648106,0.0001442823,0.0001809636,0.0000656037],"domain_scores_gemma":[0.9995664,0.00006724415,0.0001480357,0.0001168454,0.00003116167,0.00007037134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005218601,0.00001414013,0.0001715218,0.00003086062,0.000004870963,0.00008449971,0.00001750603,0.00002565196,0.9970735,0.0006874179,0.00007692685,0.001760852],"study_design_scores_gemma":[0.00002283139,0.0001052083,0.003337215,0.0000217656,0.00002879588,0.0018371,0.00004376324,0.0005408816,0.9750314,0.0001485325,0.01886949,0.00001297845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9348652,0.01142872,0.03865769,0.0005100433,0.0004297812,0.0001893251,0.002250965,0.0007694872,0.01089886],"genre_scores_gemma":[0.9505985,0.005613459,0.02807486,0.0002910921,0.00006317716,0.000284244,0.003865508,0.0003781617,0.01083092],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002243074,"threshold_uncertainty_score":0.007503808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02175990971922995,"score_gpt":0.2307175308684461,"score_spread":0.2089576211492161,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}