{"id":"W2768086853","doi":"10.1093/neuonc/nox168.209","title":"CSIG-15. PROTEOMIC AND PHOSPHOPROTEOMIC ANALYSIS OF HUMAN MEDULLOBLASTOMA REVEALS DISTINCT ACTIVATED PATHWAYS BETWEEN SUBGROUPS","year":2017,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Bioinformatics and Genomic Networks","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Medulloblastoma; Biology; Wnt signaling pathway; Phosphorylation; Computational biology; RNA; Signal transduction; Gene; Genetics; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001569431,0.0004109639,0.0004256488,0.0008871259,0.0002892949,0.0002980056,0.0003159275,0.0002472647,0.00140401],"category_scores_gemma":[0.0002121492,0.0001783218,0.0004135711,0.0008775707,0.0001612225,0.00012044,0.0002865452,0.0002737355,0.00067692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004755353,"about_ca_system_score_gemma":0.0004966969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006831385,"about_ca_topic_score_gemma":0.009315353,"domain_scores_codex":[0.9998984,0.000008268221,0.000009637864,0.00002847639,0.00003192269,0.00002322629],"domain_scores_gemma":[0.9999328,0.000008506546,0.000009739242,0.00001279911,0.00001304715,0.00002315516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007310249,0.00004102929,0.01174215,0.0001307236,0.00004710104,0.0002056165,0.00005834408,0.0002437071,0.9792028,0.00009493953,0.000689355,0.00681304],"study_design_scores_gemma":[0.00006955757,0.0007424134,0.5200657,0.00002483562,0.0002100649,0.001808557,0.000173357,0.005338522,0.4564759,0.0002924411,0.01477222,0.00002656083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9724116,0.001935287,0.002750804,0.0001211448,0.00003765704,0.00009816133,0.01982674,0.0004294185,0.002389086],"genre_scores_gemma":[0.9153273,0.001363625,0.0115541,0.0001127522,0.00001221506,0.0001230648,0.06797873,0.0001186794,0.00340958],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006831385,"threshold_uncertainty_score":0.01358324,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01761822835195826,"score_gpt":0.2745906689369452,"score_spread":0.256972440584987,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}