{"id":"W2768136090","doi":"10.1016/s0924-977x(17)31124-0","title":"Translational identification of transcriptional signatures of major depression and antidepressant response","year":2017,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Fibroblast Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Infrastructures en Biologie Santé et Agronomie; Aix-Marseille Université","keywords":"Fibroblast growth factor; Biology; FGF1; Signal transduction; GSK-3; Cell biology; Bone morphogenetic protein; Chondrocyte; Genetics; Fibroblast growth factor receptor; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003395644,0.0001612626,0.0003153813,0.0002666759,0.0001523508,0.0005653465,0.0001463075,0.0002432939,0.001924635],"category_scores_gemma":[0.0003869261,0.0001160632,0.0002278922,0.000367068,0.0001935611,0.000186509,0.000249808,0.0004358788,0.0003631358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003048114,"about_ca_system_score_gemma":0.0003863377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005736046,"about_ca_topic_score_gemma":0.001053599,"domain_scores_codex":[0.9998038,0.00003156224,0.00001322845,0.00006464902,0.00004107661,0.00004566186],"domain_scores_gemma":[0.9998145,0.0000320739,0.00006507746,0.00002460993,0.0000343852,0.00002948854],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002157609,0.0002100631,0.05018935,0.000318581,0.0001880135,0.0001995828,0.0001886871,0.0003631587,0.8706698,0.001698393,0.001843545,0.07197334],"study_design_scores_gemma":[0.0001578473,0.00105363,0.8805171,0.0001040491,0.0002118544,0.000618854,0.0004059901,0.001853723,0.09794448,0.001959418,0.01514604,0.00002693545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9750221,0.01132479,0.00320224,0.001446551,0.0002500257,0.00005400103,0.003496858,0.00007697289,0.005126449],"genre_scores_gemma":[0.9896833,0.002284082,0.001400951,0.0004996266,0.0001526821,0.00005248834,0.002990209,0.00002184662,0.002914807],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001924635,"threshold_uncertainty_score":0.006438553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01619685679566443,"score_gpt":0.3151442943192544,"score_spread":0.29894743752359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}