{"id":"W2768163240","doi":"10.1152/ajplung.00223.2017","title":"Chronic lung injury and impaired pulmonary function in a mouse model of acid ceramidase deficiency","year":2017,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; University Health Network; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Lung; Medicine; Sphingomyelin; Acid sphingomyelinase; Vascular permeability; Pulmonary edema; Pathology; Sphingolipid; Immunology; Endocrinology; Internal medicine; Biology; Biochemistry; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006875828,0.001582943,0.0008058136,0.001301871,0.0005488223,0.0005976412,0.0006626955,0.002015956,0.002002136],"category_scores_gemma":[0.0002371708,0.0005421821,0.0007513028,0.0003745738,0.000800999,0.0007080491,0.0004989026,0.001877449,0.0006490564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006004614,"about_ca_system_score_gemma":0.0003812236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006285964,"about_ca_topic_score_gemma":0.0007793249,"domain_scores_codex":[0.9992531,0.0001687501,0.00008147992,0.000215681,0.0001526198,0.0001283471],"domain_scores_gemma":[0.9995104,0.00006063573,0.0001371646,0.00006500241,0.00003393227,0.0001928108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008654807,0.0005442867,0.0004840319,0.00009421441,0.00002652806,0.0008484983,0.00008574107,0.0001726404,0.9949546,0.0003129006,0.0001500624,0.001460876],"study_design_scores_gemma":[0.000723099,0.009686123,0.02254436,0.000151051,0.0001839091,0.009665371,0.0002838694,0.007042347,0.9415233,0.0007055446,0.00742384,0.0000671635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878136,0.002561706,0.005645123,0.0005277236,0.0001203645,0.0001555522,0.0009718293,0.0004364568,0.001767601],"genre_scores_gemma":[0.9862281,0.001496171,0.004665485,0.0003463159,0.00003996549,0.0003747671,0.001158663,0.00006390562,0.005626532],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002015956,"threshold_uncertainty_score":0.006697834,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005216074396285073,"score_gpt":0.2305218995562743,"score_spread":0.2253058251599892,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}