{"id":"W2768192378","doi":"10.1071/rd17165","title":"De novo transcription of thyroid hormone receptors is essential for early bovine embryo development in vitro","year":2017,"lang":"en","type":"article","venue":"Reproduction Fertility and Development","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Korean Federation of Science and Technology Societies; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Biology; Blastocyst; Embryo; Embryogenesis; Fertilisation; Andrology; Gene knockdown; Embryonic stem cell; Cell biology; Genetics; Cell culture; Gene; Reproductive technology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002245699,0.0002939801,0.0003310286,0.0001586501,0.0001956857,0.0003986974,0.0002136424,0.0002347217,0.001916232],"category_scores_gemma":[0.0002874199,0.0002132957,0.0002713478,0.0001104148,0.0001703447,0.0001727181,0.0002638929,0.0004691683,0.001240266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004141757,"about_ca_system_score_gemma":0.000362852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003134441,"about_ca_topic_score_gemma":0.004296253,"domain_scores_codex":[0.9997178,0.00004651478,0.00003173829,0.00007591594,0.0000872232,0.00004085123],"domain_scores_gemma":[0.9997665,0.00007906706,0.00005390208,0.00002785251,0.00004159383,0.00003115038],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003493711,0.00000448729,0.0001209751,0.00003648502,0.000001539275,0.00002172837,0.00001556565,0.00001945452,0.9989154,0.00004168986,0.00003860557,0.0007490907],"study_design_scores_gemma":[0.0000157513,0.0001913264,0.01446463,0.0000263719,0.0000257176,0.0002740096,0.0000549538,0.0008252931,0.969734,0.00006574971,0.01431372,0.000008664632],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9255764,0.02506105,0.03320642,0.0003981488,0.0002302642,0.0001041038,0.003457268,0.00039063,0.01157572],"genre_scores_gemma":[0.9680966,0.005117727,0.009257992,0.0001867716,0.0000334629,0.00007532657,0.003648011,0.0001130124,0.01347109],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003134441,"threshold_uncertainty_score":0.00641042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03078084011828154,"score_gpt":0.2832257983801808,"score_spread":0.2524449582618993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}