{"id":"W2768192378","doi":"10.1071/rd17165","title":"De novo transcription of thyroid hormone receptors is essential for early bovine embryo development in vitro","year":2017,"lang":"en","type":"article","venue":"Reproduction Fertility and Development","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Korean Federation of Science and Technology Societies; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Biology; Blastocyst; Embryo; Embryogenesis; Fertilisation; Andrology; Gene knockdown; Embryonic stem cell; Cell biology; Genetics; Cell culture; Gene; Reproductive technology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001660571,0.0001993588,0.0004276208,0.0001187777,0.0003795927,0.00002542638,0.0001078969,0.000178361,0.00002701017],"category_scores_gemma":[0.0005190427,0.0001822747,0.00006654146,0.00007249877,0.0002616306,0.0001987459,0.00005369748,0.0001777558,0.000004660817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001876476,"about_ca_system_score_gemma":0.0003726342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006614265,"about_ca_topic_score_gemma":0.00001515278,"domain_scores_codex":[0.9979028,0.00005609566,0.0006484474,0.0008942916,0.0001944839,0.000303862],"domain_scores_gemma":[0.9986617,0.00001807673,0.0002104669,0.0007303926,0.0002708333,0.0001085353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.04723418,0.0008215861,0.08498721,0.0003935773,0.0001656166,0.000003019674,0.006566426,7.09768e-7,0.7536095,0.000009549755,0.0001212919,0.1060874],"study_design_scores_gemma":[0.001031206,0.0001138065,0.5596607,0.00002221483,0.00001579526,0.000007912212,0.00006555694,0.000004202106,0.4344213,0.00008136301,0.004478363,0.00009759294],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942894,0.0008919245,0.002021137,0.001381301,0.0003629172,0.0008823509,0.000005456201,0.00003401193,0.0001314743],"genre_scores_gemma":[0.9887497,0.00006125584,0.01003292,0.00004906175,0.00009451298,0.0001095158,0.00004125605,0.00001248952,0.0008493109],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4746735,"threshold_uncertainty_score":0.7432946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03078084011828154,"score_gpt":0.2832257983801808,"score_spread":0.2524449582618993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}