{"id":"W2768255762","doi":"10.1016/j.freeradbiomed.2017.10.110","title":"Contribution of Thioredoxin1 in Modulation of Lysosomal Autophagy","year":2017,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Autophagy; Oxidative stress; Thioredoxin reductase; Thioredoxin; Cell biology; Programmed cell death; Apoptosis; Chemistry; Proteasome; Lysosome; Biochemistry; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003012352,0.0002418724,0.0002948584,0.0001695155,0.0003026564,0.0005231041,0.0002054803,0.0004055848,0.001023892],"category_scores_gemma":[0.0001598586,0.0001120539,0.0002691202,0.0001009784,0.0002724558,0.0004191793,0.0002229095,0.0005391267,0.0001782956],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004805661,"about_ca_system_score_gemma":0.0002537808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003134598,"about_ca_topic_score_gemma":0.0003150846,"domain_scores_codex":[0.9999124,0.00002063225,0.000007240287,0.00001752057,0.00001416993,0.00002801576],"domain_scores_gemma":[0.9999121,0.00001646941,0.00001874748,0.00001416841,0.000017509,0.00002097531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001003352,0.00004456277,0.0004929482,0.00008540314,0.00001730613,0.0001470307,0.00003206447,0.000127575,0.9927643,0.001216275,0.00008411342,0.003985076],"study_design_scores_gemma":[0.00003512857,0.0002750148,0.006837294,0.00001373473,0.00004187421,0.0003513013,0.0000751766,0.001227957,0.9878492,0.0006118373,0.002671694,0.000009694017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862217,0.009047458,0.00198739,0.0005804687,0.00008572298,0.00001730905,0.0001036503,0.00005648447,0.001899929],"genre_scores_gemma":[0.9965245,0.001385264,0.0004584497,0.00004962384,0.00001456606,0.000005672036,0.00006857429,0.00000692482,0.001486416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001023892,"threshold_uncertainty_score":0.003486753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01035858290930498,"score_gpt":0.3058042818431542,"score_spread":0.2954456989338493,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}