{"id":"W2768339478","doi":"10.1002/path.5008","title":"IGF1R signalling in testicular germ cell tumour cells impacts on cell survival and acquired cisplatin resistance","year":2017,"lang":"en","type":"article","venue":"The Journal of Pathology","topic":"Testicular diseases and treatments","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council Canada; University College London; National Institute for Health and Care Research; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research","keywords":"Cisplatin; Germ cell; Insulin-like growth factor 1 receptor; Testicular cancer; Cell; Acquired resistance; Cell biology; Cancer research; Biology; Oncology; Cancer; Medicine; Chemotherapy; Genetics; Receptor; Growth factor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000764127,0.0001433608,0.0002621518,0.0001672306,0.0001024018,0.0003676404,0.0001293649,0.0001862655,0.001675208],"category_scores_gemma":[0.00009719972,0.00008187301,0.0001946997,0.0001682409,0.0001316548,0.0001287301,0.0001475564,0.0004483731,0.0003577053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003230128,"about_ca_system_score_gemma":0.0001930938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001076672,"about_ca_topic_score_gemma":0.001424218,"domain_scores_codex":[0.9999039,0.00001070323,0.000007981181,0.00001920234,0.00003461327,0.00002356394],"domain_scores_gemma":[0.9999512,0.000007886502,0.0000096817,0.000006010902,0.00000849328,0.00001674382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002237715,0.00004560297,0.002351429,0.0001071389,0.00001555851,0.0002151437,0.00005524173,0.0002115912,0.9920752,0.0001362521,0.0002347931,0.004328303],"study_design_scores_gemma":[0.00005691525,0.001162022,0.0821073,0.00002046411,0.00006603941,0.001637136,0.0002231285,0.002351784,0.8986357,0.0001369913,0.0135851,0.00001743623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938392,0.002613273,0.0007201749,0.00009469027,0.00002979388,0.00002338486,0.0009119714,0.00008587002,0.001681778],"genre_scores_gemma":[0.9963691,0.0007677294,0.0003406857,0.00005665683,0.000003457302,0.00001852203,0.000844587,0.000009590721,0.00158974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001675208,"threshold_uncertainty_score":0.005604148,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01974013265774983,"score_gpt":0.2816967491206269,"score_spread":0.2619566164628771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}