{"id":"W2768339478","doi":"10.1002/path.5008","title":"IGF1R signalling in testicular germ cell tumour cells impacts on cell survival and acquired cisplatin resistance","year":2017,"lang":"en","type":"article","venue":"The Journal of Pathology","topic":"Testicular diseases and treatments","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council Canada; University College London; National Institute for Health and Care Research; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research","keywords":"Cisplatin; Germ cell; Insulin-like growth factor 1 receptor; Testicular cancer; Cell; Acquired resistance; Cell biology; Cancer research; Biology; Oncology; Cancer; Medicine; Chemotherapy; Genetics; Receptor; Growth factor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006607941,0.0001528691,0.0003752183,0.00008167492,0.0001465703,0.00002843375,0.0001716019,0.00006995854,0.00001786808],"category_scores_gemma":[0.0003259336,0.00009339338,0.00008380788,0.00003705559,0.0001250551,0.00006121081,0.00004629056,0.0001991218,0.000009609445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004651303,"about_ca_system_score_gemma":0.00009834323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001575837,"about_ca_topic_score_gemma":0.00002083092,"domain_scores_codex":[0.9988911,0.0001879137,0.0003340317,0.0001261262,0.0002182135,0.0002426856],"domain_scores_gemma":[0.9984729,0.0003338621,0.0006292814,0.0003081733,0.00008617654,0.0001695788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002214641,0.001058578,0.1045951,0.0001909556,0.00006924913,0.02600899,0.0007532138,0.000277559,0.8639493,0.00004560574,0.0002376018,0.0005992574],"study_design_scores_gemma":[0.006428658,0.001410658,0.9390101,0.0004236749,0.0005742246,0.0008228613,0.0002197865,0.0001274849,0.05007594,0.0006908036,0.00005586764,0.0001598808],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995801,0.002303242,0.00008003454,0.0004787064,0.0001571115,0.0001524155,0.000008833039,0.000004817517,0.0010138],"genre_scores_gemma":[0.9986652,0.0003201744,0.000597527,0.00009962627,0.0001088993,9.870049e-7,0.000001221792,0.00001829521,0.0001881438],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8344151,"threshold_uncertainty_score":0.3808472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01974013265774983,"score_gpt":0.2816967491206269,"score_spread":0.2619566164628771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}