{"id":"W2768413036","doi":"10.18433/j38p9r","title":"Thiazolidinedione or Rhodanine: A Study on Synthesis and Anticancer Activity Comparison of Novel Thiazole Derivatives","year":2017,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ankara Universitesi","keywords":"Rhodanine; Chemistry; Cytotoxicity; Sulforhodamine B; Thiazole; IC50; Knoevenagel condensation; Cell culture; Cancer cell lines; Thiazolidinedione; Combinatorial chemistry; In vitro; Pharmacology; Stereochemistry; Cancer cell; Cancer; Biochemistry; Medicine; Internal medicine; Endocrinology; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001507187,0.0002392182,0.0006940205,0.00008295681,0.0006246563,0.0001681015,0.0008827259,0.00005547887,0.0006979733],"category_scores_gemma":[0.001888091,0.0001312191,0.0001423632,0.000144177,0.001144098,0.0005596892,0.0002517435,0.0004801115,0.000001630799],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000386467,"about_ca_system_score_gemma":0.0001111832,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000398921,"about_ca_topic_score_gemma":0.000004585662,"domain_scores_codex":[0.9978626,0.000114374,0.0005411244,0.0003365181,0.0008070376,0.0003383883],"domain_scores_gemma":[0.9966274,0.001776146,0.0009938031,0.0002009621,0.0001412478,0.0002603737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00139762,0.003624145,0.2266137,0.00004796853,0.0001182452,0.0000137027,0.000190798,0.000008774976,0.678664,0.00004190886,0.00003960602,0.08923952],"study_design_scores_gemma":[0.001693476,0.0004343776,0.07414214,0.0001239851,0.0001688668,0.00002822938,0.0006404106,0.003589635,0.9172345,0.00002135877,0.001729889,0.000193122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995547,0.0002028158,0.00006832017,0.00188663,0.0001614203,0.0001041997,0.00001649906,0.000012438,0.002000685],"genre_scores_gemma":[0.9989266,0.0003032891,0.0003810817,0.00007385878,0.0002818511,0.000005874398,4.394882e-8,0.000007669606,0.00001968542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2385705,"threshold_uncertainty_score":0.7642318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3014512375995426,"score_gpt":0.490373635831109,"score_spread":0.1889223982315664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}