{"id":"W2768421721","doi":"10.1038/nbt.4024","title":"Global landscape of cell envelope protein complexes in Escherichia coli","year":2017,"lang":"en","type":"article","venue":"Nature Biotechnology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":147,"is_retracted":false,"has_abstract":false,"ca_institutions":"Carleton University; University of Saskatchewan; Armand Frappier Museum; Hospital for Sick Children; Institut National de la Recherche Scientifique; University of Toronto; University of Regina","funders":"National Institute of General Medical Sciences","keywords":"Periplasmic space; Bacterial outer membrane; Escherichia coli; Interactome; Cell envelope; Inner membrane; Membrane transport protein; Transport protein; Membrane protein; Biology; Biochemistry; Cell biology; Chemistry; Membrane; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002394281,0.0002667618,0.0003738364,0.0007189,0.0007091965,0.001568618,0.000328645,0.0005127437,0.001573766],"category_scores_gemma":[0.000581529,0.0003022219,0.000215816,0.000624759,0.0005422351,0.0008887563,0.0004714875,0.0004637771,0.0003596963],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009264673,"about_ca_system_score_gemma":0.0003067933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001675771,"about_ca_topic_score_gemma":0.003396241,"domain_scores_codex":[0.9998578,0.00001699763,0.00000653349,0.00005343249,0.00002977445,0.00003541358],"domain_scores_gemma":[0.9997032,0.0000665646,0.00005607163,0.00002307183,0.00004197405,0.0001090071],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00135194,0.0001311589,0.03556302,0.0002641529,0.0002752577,0.0003682809,0.0003514432,0.02171731,0.9064537,0.0137712,0.001509607,0.01824303],"study_design_scores_gemma":[0.0001133741,0.0007405082,0.4684001,0.0000746019,0.0004966343,0.001380697,0.002800916,0.1626853,0.3006709,0.0364193,0.02602928,0.0001883983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946607,0.001214645,0.001334588,0.0003771385,0.000004996592,0.000003424163,0.0002839031,0.00005108743,0.002069627],"genre_scores_gemma":[0.9978139,0.0004979623,0.000617801,0.00005538738,0.000004730763,0.000005914295,0.0004115946,0.00002169055,0.0005709545],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001675771,"threshold_uncertainty_score":0.006722033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005441096643477696,"score_gpt":0.2362458957984431,"score_spread":0.2308047991549654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}