{"id":"W2768432304","doi":"10.1002/prot.25427","title":"Crystal structure of the Legionella effector Lem22","year":2017,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Center for Research Resources; National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Effector; Legionella pneumophila; Legionella; Biology; Pathogen; Protein structure; Microbiology; Computational biology; Peptide sequence; Cell biology; Genetics; Bacteria; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006674664,0.0001500927,0.0001301146,0.00003097302,0.0005163401,0.0001027883,0.0003010537,0.0001777614,0.00003401557],"category_scores_gemma":[0.0001069278,0.00008868946,0.00007339979,0.00004434273,0.0002878325,0.00001853258,0.0002756683,0.0001717825,0.000001229083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007606673,"about_ca_system_score_gemma":0.00006541846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000271602,"about_ca_topic_score_gemma":0.00005927715,"domain_scores_codex":[0.9992296,0.0000249057,0.0002010341,0.0001404195,0.0002204564,0.0001836316],"domain_scores_gemma":[0.9990092,0.000004850815,0.0002417269,0.0005803767,0.00009895668,0.00006488847],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001411831,0.00001115903,0.0126353,0.0002340249,0.00005721034,2.830782e-7,0.00008826504,0.00001235617,0.9812555,0.0003076667,0.00120972,0.004047328],"study_design_scores_gemma":[0.002061291,0.0006540315,0.1153555,0.00007978559,0.00006227584,0.0001028246,0.0002518276,0.0008350798,0.8541742,0.001341903,0.02466034,0.0004209687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965792,0.0001042677,0.001214954,0.00027766,0.0004130506,0.0005571478,0.0001226458,0.000008078436,0.0007229914],"genre_scores_gemma":[0.998531,0.00002784484,0.0007761195,0.0001131072,0.0002245702,0.000003738425,0.0000424433,0.00001045964,0.0002706714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1270813,"threshold_uncertainty_score":0.3971323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008273605052029741,"score_gpt":0.2343502349428804,"score_spread":0.2260766298908507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}