{"id":"W2768434803","doi":"10.1002/brb3.896","title":"Longitudinal evaluation of Tau‐P301L transgenic mice reveals no cognitive impairments at 17 months of age","year":2017,"lang":"en","type":"article","venue":"Brain and Behavior","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Occupational Cancer Research Centre; University of Toronto; University of British Columbia","funders":"Medical Research Council; Alzheimer Society; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; University of Cambridge; Wellcome Trust","keywords":"Tauopathy; Frontotemporal dementia; Neuroscience; Psychology; Tau protein; Dementia; Cognition; Atrophy; Parkinsonism; Genetically modified mouse; Alzheimer's disease; Biology; Disease; Transgene; Pathology; Medicine; Neurodegeneration; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006111608,0.0009550711,0.000727722,0.001601056,0.0006028836,0.0006481397,0.0005131317,0.0009065506,0.002780855],"category_scores_gemma":[0.0002960133,0.0003120482,0.0006742252,0.0003914687,0.0004989193,0.0005812783,0.0003996091,0.001835757,0.00139837],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004626836,"about_ca_system_score_gemma":0.0004028766,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001838504,"about_ca_topic_score_gemma":0.003389286,"domain_scores_codex":[0.9996431,0.00002031142,0.0000473334,0.0001017927,0.00007808158,0.0001094556],"domain_scores_gemma":[0.9986864,0.00009957836,0.000452235,0.00006297505,0.0002707326,0.0004280458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001215835,0.0008209212,0.007790084,0.0000644966,0.00005811482,0.0008471554,0.0002884259,0.00005664929,0.9842234,0.00008321325,0.0003293186,0.004222357],"study_design_scores_gemma":[0.0002228602,0.006610704,0.1610421,0.0001261977,0.0004133406,0.004599634,0.000549552,0.00119282,0.8189646,0.0003059335,0.005880385,0.00009174407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897619,0.0007798231,0.002365008,0.000127551,0.00005584996,0.0001110529,0.004756809,0.0002967698,0.0017453],"genre_scores_gemma":[0.9651685,0.001363272,0.004589834,0.0002665528,0.00003994174,0.0005498878,0.01235007,0.0002548352,0.01541717],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002780855,"threshold_uncertainty_score":0.009302914,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09004074508796278,"score_gpt":0.407044443104162,"score_spread":0.3170036980161992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}