{"id":"W2768553098","doi":"10.1038/s41598-017-16734-2","title":"Protein Structure Insights into the Bilayer Interactions of the Saposin-Like Domain of Solanum tuberosum Aspartic Protease","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Biochemical and Structural Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Protein secondary structure; Biophysics; Protein structure; Bilayer; Protease; Active site; Lipid bilayer; Chemistry; Circular dichroism; Protein folding; Biochemistry; Biology; Membrane; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004459254,0.0001334602,0.00008489957,0.00008111563,0.00008161601,0.000109468,0.00008834149,0.000141059,0.0005467656],"category_scores_gemma":[0.00006544679,0.00005855875,0.0001202567,0.00008025835,0.00008409838,0.0001142269,0.00007052115,0.0002631212,0.0001580207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001161557,"about_ca_system_score_gemma":0.00009537189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004315466,"about_ca_topic_score_gemma":0.0005597731,"domain_scores_codex":[0.999984,0.000002859982,9.278259e-7,0.000003236717,0.000005966163,0.000002970017],"domain_scores_gemma":[0.9999806,0.000004881122,0.000004685479,0.000001182005,0.000003383806,0.000005392368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004918432,0.000009194314,0.00029412,0.00003056112,0.000003079783,0.0001245447,0.0000280169,0.0001692285,0.9984187,0.0001053851,0.00001529405,0.000752706],"study_design_scores_gemma":[0.00002823975,0.0003915049,0.03941311,0.0000220196,0.00004420838,0.002487647,0.0003704471,0.01468701,0.9357194,0.001033034,0.0057906,0.0000128847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969215,0.000503486,0.001859667,0.00004658425,0.000004501606,0.000003973328,0.00006157525,0.00001173708,0.0005870161],"genre_scores_gemma":[0.9973029,0.0004002216,0.001654892,0.00002522824,0.000002511926,0.000001990437,0.0001974198,0.000003484462,0.0004113593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005467656,"threshold_uncertainty_score":0.001829088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007578689857765229,"score_gpt":0.2358651805579675,"score_spread":0.2282864907002023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}