{"id":"W2768721195","doi":"10.2174/1385272819666140201002503","title":"Biologically Active Synthetic Anionophores","year":2014,"lang":"en","type":"article","venue":"Current Organic Chemistry","topic":"Molecular Sensors and Ion Detection","field":"Chemistry","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Biological activity; Ion channel; Transmembrane protein; Transmembrane channels; Cancer cell; Biophysics; Computational biology; Combinatorial chemistry; Biochemistry; Nanotechnology; Cancer; In vitro; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00006475744,0.0001975529,0.0001772765,0.00001186845,0.00009459508,0.00003306187,0.0002221557,0.0001631525,0.01409631],"category_scores_gemma":[0.0003014985,0.0001758517,0.0001038744,0.00009906191,0.00007082951,0.00002859771,0.00008616001,0.0003053337,0.0001616079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007114979,"about_ca_system_score_gemma":0.00002519155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001485336,"about_ca_topic_score_gemma":2.528647e-7,"domain_scores_codex":[0.99896,0.00001492055,0.0002037161,0.0004130152,0.000161996,0.0002463957],"domain_scores_gemma":[0.9992605,0.00004859151,0.0001052627,0.0004039458,0.00005611106,0.0001255219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001697222,0.0000772663,0.00009081229,0.0001030892,0.00001291619,0.000001093054,0.00001861429,9.563469e-7,0.9561184,0.0000255896,0.0002955485,0.04323871],"study_design_scores_gemma":[0.0002488839,0.000008815881,0.0001200125,0.00005168292,0.00001918214,0.0000238175,0.00003457015,0.0002450061,0.901812,0.0002059722,0.09700884,0.0002212441],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9756567,0.0003050306,0.0006543465,0.00008186385,0.000217954,0.00003137471,0.00001271299,0.0002044442,0.0228355],"genre_scores_gemma":[0.9986373,0.0001133788,0.00003273444,0.00002214605,0.0004146255,0.000009624754,0.00004446985,0.00002541301,0.0007003126],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09671329,"threshold_uncertainty_score":0.986805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009100537216148447,"score_gpt":0.2205194660256187,"score_spread":0.2114189288094702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}