{"id":"W2768802022","doi":"10.1159/000481286","title":"The Membrane Attack Complex/Perforin Superfamily","year":2017,"lang":"en","type":"article","venue":"Microbial Physiology","topic":"Pancreatitis Pathology and Treatment","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Wilfrid Laurier University","funders":"National Institute of General Medical Sciences","keywords":"Biology; Complement membrane attack complex; Protein family; SUPERFAMILY; Perforin; Cytolysin; Protein domain; Genetics; Computational biology; Gene; Immune system; Complement system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009625887,0.0001458666,0.000316186,0.00001759937,0.001065072,0.00002243407,0.0002314594,0.0001132488,0.0001574622],"category_scores_gemma":[0.00006165545,0.00009184041,0.0001059897,0.00001709367,0.0006656898,0.0000401355,0.0001133098,0.0001744865,0.0006124088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003343391,"about_ca_system_score_gemma":0.00004814492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000126401,"about_ca_topic_score_gemma":0.00009379222,"domain_scores_codex":[0.9991526,0.0000638673,0.0001531464,0.0002592843,0.00004568406,0.0003254043],"domain_scores_gemma":[0.9989524,0.00007070872,0.00007791158,0.0007937634,0.00004243418,0.0000627757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003520216,0.0001042295,0.005618972,0.00001357476,0.000118805,0.00006520472,0.00005764935,0.000001658529,0.9847513,0.0004891891,0.006719491,0.001707931],"study_design_scores_gemma":[0.002313754,0.0003456414,0.9005138,0.00001927349,0.00009349488,0.0002292958,0.00001857083,0.00001751049,0.04602024,0.000167943,0.05014656,0.0001139504],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875018,0.0001505251,0.000002631618,0.002504448,0.0004587874,0.0002307478,0.0000197582,0.00003557325,0.009095712],"genre_scores_gemma":[0.9956047,0.0002231308,0.0001822774,0.0007297192,0.0003479476,0.00001981161,0.00006382919,0.00001429051,0.002814291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.938731,"threshold_uncertainty_score":0.8191778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04586906105684497,"score_gpt":0.3146497766815943,"score_spread":0.2687807156247494,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}