{"id":"W2768980689","doi":"10.1158/1538-7445.sabcs16-p4-15-01","title":"Abstract P4-15-01: Cost-effectiveness of pre-implantation genetic diagnosis for BRCA mutation carriers","year":2017,"lang":"en","type":"article","venue":"Cancer Research","topic":"Biomedical Ethics and Regulation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo; Sunnybrook Health Science Centre","funders":"","keywords":"BRCA mutation; Medicine; Breast cancer; Cost effectiveness; Cancer; Oncology; Gynecology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002165881,0.0006836431,0.0008916058,0.0006794287,0.0002262473,0.001247526,0.0009775441,0.00128694,0.01408983],"category_scores_gemma":[0.006664103,0.0004177829,0.00178334,0.0005080969,0.0003616431,0.0008418976,0.000580113,0.001254171,0.0004128926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003170527,"about_ca_system_score_gemma":0.00304495,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01672317,"about_ca_topic_score_gemma":0.007211908,"domain_scores_codex":[0.9993846,0.0003954312,0.00001640108,0.00006133785,0.00005319554,0.00008887997],"domain_scores_gemma":[0.9954926,0.003879244,0.0002366046,0.00007101719,0.0001480467,0.0001723964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001335162,0.0001823006,0.004747699,0.0003315385,0.0002255207,0.000102202,0.00002305842,0.9773374,0.0003236349,0.003697148,0.002319819,0.009374504],"study_design_scores_gemma":[0.0007089833,0.001404009,0.006842529,0.0002792026,0.0005465806,0.0001666141,0.00006441427,0.9813037,0.0007421271,0.005776636,0.002124889,0.0000402363],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9054838,0.003964028,0.04709083,0.003753976,0.0001729842,0.0009105144,0.01213256,0.0002902576,0.02620091],"genre_scores_gemma":[0.991693,0.000529046,0.004254989,0.0001190792,0.00001925258,0.0001826213,0.001187973,0.00001936847,0.001994742],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.01672317,"threshold_uncertainty_score":0.04713517,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1634230915910374,"score_gpt":0.5106488479463663,"score_spread":0.3472257563553289,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}