{"id":"W2769194636","doi":"10.1016/j.immuni.2017.11.007","title":"Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies","year":2017,"lang":"en","type":"article","venue":"Immunity","topic":"Malaria Research and Control","field":"Medicine","cited_by":148,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"Albert Schweitzer Ziekenhuis; Argonne National Laboratory; Government of Saskatchewan; Agence Nationale de la Recherche; Western Economic Diversification Canada; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Studienstiftung des Deutschen Volkes; National Research Council Canada; Canada Foundation for Innovation; National Institutes of Health; Office of Science; University of Saskatchewan","keywords":"Circumsporozoite protein; Biology; Antibody; Plasmodium falciparum; Epitope; Antigen; Virology; Malaria; Immunology; Humoral immunity","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0004671173,0.0001572365,0.0003390808,0.00007933846,0.001378973,0.0001937941,0.0003946836,0.0001236809,0.0001500905],"category_scores_gemma":[0.001015269,0.0001219236,0.0001155879,0.00004245674,0.0002948611,0.0002782136,0.000204227,0.0009486887,0.00004728345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003612377,"about_ca_system_score_gemma":0.0001118742,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002147457,"about_ca_topic_score_gemma":0.0001839458,"domain_scores_codex":[0.9987876,0.0001685009,0.0001711142,0.0001943227,0.0003185874,0.0003599066],"domain_scores_gemma":[0.9985337,0.00004503253,0.0001338398,0.0009337955,0.0002326555,0.0001209335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001190532,0.0004004554,0.1112236,0.0001257535,0.0004631354,0.0002179718,0.0007719818,2.75932e-7,0.8729427,0.002464043,0.0002892185,0.009910328],"study_design_scores_gemma":[0.002906566,0.0004250762,0.9704365,0.00008707693,0.00004269856,0.00002394825,0.0001451164,0.00001497204,0.02501853,0.0004796928,0.0002882368,0.0001316029],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893295,0.0003290325,0.00001351389,0.002067225,0.0002413781,0.0007486007,0.00001071382,0.00006109165,0.007198927],"genre_scores_gemma":[0.9983284,0.00001539804,0.00006290237,0.00006510648,0.0003890694,0.00004206767,0.00002215528,0.00001433197,0.001060568],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8592129,"threshold_uncertainty_score":0.9999211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0335679390992422,"score_gpt":0.351405150202544,"score_spread":0.3178372111033018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}