{"id":"W2769194636","doi":"10.1016/j.immuni.2017.11.007","title":"Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies","year":2017,"lang":"en","type":"article","venue":"Immunity","topic":"Malaria Research and Control","field":"Medicine","cited_by":148,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"Albert Schweitzer Ziekenhuis; Argonne National Laboratory; Government of Saskatchewan; Agence Nationale de la Recherche; Western Economic Diversification Canada; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Studienstiftung des Deutschen Volkes; National Research Council Canada; Canada Foundation for Innovation; National Institutes of Health; Office of Science; University of Saskatchewan","keywords":"Circumsporozoite protein; Biology; Antibody; Plasmodium falciparum; Epitope; Antigen; Virology; Malaria; Immunology; Humoral immunity","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002682717,0.0002459417,0.0001752302,0.0002473225,0.0001156611,0.000341905,0.0001308971,0.0003092563,0.003782754],"category_scores_gemma":[0.0004182178,0.0001764538,0.0001495989,0.00006349233,0.0002532158,0.0001825113,0.0003226631,0.001007026,0.000573118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001624801,"about_ca_system_score_gemma":0.0001470084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008895352,"about_ca_topic_score_gemma":0.0001747667,"domain_scores_codex":[0.9997539,0.00007761335,0.00000965139,0.00003805204,0.00004007614,0.00008069789],"domain_scores_gemma":[0.9997236,0.0001024531,0.00003632185,0.00005143123,0.00002079207,0.0000653653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00133538,0.0007351732,0.002120512,0.00007391875,0.00001901857,0.0002422431,0.00005699912,0.0001222599,0.9832023,0.0005571887,0.0006211063,0.01091399],"study_design_scores_gemma":[0.0007140414,0.01188141,0.09497432,0.00005258076,0.00009878667,0.003901135,0.0002746525,0.002208379,0.8710142,0.001456599,0.01340046,0.00002342867],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949303,0.0006035095,0.001163663,0.0001411984,0.0000863117,0.00003116343,0.00005966988,0.00007830984,0.002905827],"genre_scores_gemma":[0.9975852,0.0001835158,0.0003346953,0.0001168414,0.00005709711,0.00001632514,0.00008883415,0.00001066935,0.001606843],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003782754,"threshold_uncertainty_score":0.01265454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0335679390992422,"score_gpt":0.351405150202544,"score_spread":0.3178372111033018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}