{"id":"W2769279227","doi":"10.1002/btpr.2589","title":"A factorial design to identify process parameters affecting whole mechanically disrupted rat pancreata in a perfusion bioreactor","year":2017,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health and Social Services Centre University Institute of Geriatrics of Sherbrooke; Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Université de Sherbrooke","keywords":"Insulin; Bioreactor; Glucagon; Internal medicine; IBMX; Biology; Endocrinology; Perfusion; Factorial experiment; Chemistry; Stimulation; Forskolin; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003557524,0.0024058,0.003464423,0.001370586,0.0008123005,0.00169835,0.001336008,0.001234028,0.00368364],"category_scores_gemma":[0.002228468,0.0007353454,0.00234858,0.001068881,0.0008950905,0.0006222922,0.0009326827,0.002847709,0.0005694111],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001275035,"about_ca_system_score_gemma":0.002002697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001061868,"about_ca_topic_score_gemma":0.0009913071,"domain_scores_codex":[0.9945279,0.001206607,0.0007254963,0.001334231,0.001363194,0.0008426674],"domain_scores_gemma":[0.9969381,0.00112317,0.0007564555,0.0002851432,0.0005921865,0.0003049935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03046125,0.008910835,0.001863753,0.001849181,0.000416684,0.0001055765,0.000260782,0.003287173,0.9315123,0.0004092236,0.0002543883,0.02066888],"study_design_scores_gemma":[0.006914305,0.3492379,0.04063958,0.0001954458,0.00347503,0.0001852855,0.0004934618,0.01695467,0.5622165,0.0008709202,0.01846518,0.0003516398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9357311,0.002496203,0.04719255,0.0001705155,0.0007314847,0.009776252,0.001554642,0.0004356272,0.001911619],"genre_scores_gemma":[0.7610928,0.002772292,0.1718061,0.0006449227,0.0002574151,0.05340368,0.002001726,0.0002047585,0.007816331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00368364,"threshold_uncertainty_score":0.01881421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04221040164898122,"score_gpt":0.3514696394699211,"score_spread":0.3092592378209399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}