{"id":"W2769332703","doi":"10.1001/jama.2017.17070","title":"Effect of Oral Insulin on Prevention of Diabetes in Relatives of Patients With Type 1 Diabetes","year":2017,"lang":"en","type":"article","venue":"JAMA","topic":"Diabetes Management and Research","field":"Medicine","cited_by":203,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Center for Research Resources; National Institute of Allergy and Infectious Diseases; University of California, Los Angeles; National Institutes of Health; Turun Yliopisto; Universiteit Leiden; Children's National Hospital; University of Washington; Children's Mercy Hospital; National Center for Advancing Translational Sciences; Leids Universitair Medisch Centrum; Joslin Diabetes Center; North Carolina State University; University of California, San Francisco; Baylor University; University of Minnesota; Georgetown University; University of Bristol; Wake Forest University; Eli Lilly and Company; University of Miami; University of South Florida; Lunds Universitet; King's College London; George Washington University; University of Pennsylvania; University of Toronto; Yale University; Vanderbilt University; Helsingin Yliopisto; Harvard University; University of Pittsburgh; Children's Hospital Los Angeles; Cleveland Clinic; Emory University","keywords":"Medicine; Diabetes mellitus; Insulin; Internal medicine; Interquartile range; Type 2 diabetes; Autoantibody; Type 1 diabetes; Placebo; Randomization; Randomized controlled trial; Endocrinology; Antibody; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004777778,0.00007232696,0.0003052815,0.0001515764,0.00001831442,0.000006125964,0.0001075498,0.00004938113,0.00003693843],"category_scores_gemma":[0.0006778885,0.00004607897,0.00004163862,0.0001082079,0.0001397211,0.0001084788,0.00006083764,0.00009968183,0.000004151891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001123289,"about_ca_system_score_gemma":0.00001358566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005882296,"about_ca_topic_score_gemma":0.000003048058,"domain_scores_codex":[0.9992316,0.00009018125,0.000175409,0.0001052604,0.0002677392,0.0001297758],"domain_scores_gemma":[0.9992372,0.0001313299,0.0002109998,0.0002790173,0.0001163842,0.00002507746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005406693,0.0003437919,0.9170607,0.0007214702,0.00008524932,3.29295e-7,0.0000461717,0.000003197638,0.001095005,0.00004041225,0.00006598554,0.07999703],"study_design_scores_gemma":[0.004353066,0.007160486,0.9453971,0.0008980309,0.00004646182,9.710186e-10,0.000005038622,0.0001174354,0.04186689,0.00007347728,0.00004342081,0.00003853378],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995567,0.00005733203,2.030918e-7,0.00006381305,0.00003662358,0.0004495687,0.000004167922,0.000003845537,0.003817497],"genre_scores_gemma":[0.9993786,0.000006601859,0.00005425101,0.00000431549,0.00001057975,0.000007497981,0.00002058226,0.000008829352,0.0005087346],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0799585,"threshold_uncertainty_score":0.1879046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01388357127672562,"score_gpt":0.3053647329404359,"score_spread":0.2914811616637102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}