{"id":"W2769332703","doi":"10.1001/jama.2017.17070","title":"Effect of Oral Insulin on Prevention of Diabetes in Relatives of Patients With Type 1 Diabetes","year":2017,"lang":"en","type":"article","venue":"JAMA","topic":"Diabetes Management and Research","field":"Medicine","cited_by":203,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Center for Research Resources; National Institute of Allergy and Infectious Diseases; University of California, Los Angeles; National Institutes of Health; Turun Yliopisto; Universiteit Leiden; Children's National Hospital; University of Washington; Children's Mercy Hospital; National Center for Advancing Translational Sciences; Leids Universitair Medisch Centrum; Joslin Diabetes Center; North Carolina State University; University of California, San Francisco; Baylor University; University of Minnesota; Georgetown University; University of Bristol; Wake Forest University; Eli Lilly and Company; University of Miami; University of South Florida; Lunds Universitet; King's College London; George Washington University; University of Pennsylvania; University of Toronto; Yale University; Vanderbilt University; Helsingin Yliopisto; Harvard University; University of Pittsburgh; Children's Hospital Los Angeles; Cleveland Clinic; Emory University","keywords":"Medicine; Diabetes mellitus; Insulin; Internal medicine; Interquartile range; Type 2 diabetes; Autoantibody; Type 1 diabetes; Placebo; Randomization; Randomized controlled trial; Endocrinology; Antibody; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007640765,0.0003434574,0.0007209892,0.0001842597,0.0002905985,0.0002691728,0.0002144456,0.0005081642,0.002070868],"category_scores_gemma":[0.003591879,0.0001615324,0.0006912746,0.0001750345,0.0001444779,0.0002021069,0.0002110496,0.0005265872,0.0001291521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002713628,"about_ca_system_score_gemma":0.0003702018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008767362,"about_ca_topic_score_gemma":0.002079168,"domain_scores_codex":[0.9997033,0.0001654841,0.00003023269,0.00003591474,0.00002876178,0.0000362564],"domain_scores_gemma":[0.9985133,0.0006601424,0.000410438,0.00006428491,0.00005454614,0.0002974007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6521411,0.01019969,0.1417981,0.001684717,0.001766374,0.0003137019,0.0002208733,0.0005134816,0.001937298,0.00008730139,0.001146247,0.1881911],"study_design_scores_gemma":[0.09770031,0.3147793,0.5730258,0.0009723406,0.005149417,0.0009274074,0.0005440035,0.001626266,0.002018976,0.0004355084,0.002762888,0.00005789007],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99361,0.005000384,0.00005637464,0.000192123,0.0001101165,0.00005120531,0.0000747404,0.00001029268,0.000894747],"genre_scores_gemma":[0.9981461,0.001190572,0.0002141867,0.0001051102,0.00006152601,0.00003755726,0.00005127637,0.000001016933,0.0001927745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002070868,"threshold_uncertainty_score":0.006927788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01388357127672562,"score_gpt":0.3053647329404359,"score_spread":0.2914811616637102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}